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HPPE

产品详情:

更新时间: 2024-07-17 15:06:27

CAS号:1325721-55-8

常用名: HPPE

价格:
$1080.0/100mg

纯度: 98.0%

备货期: 3天

库存: 3

产品页: https://www.dcchemicals.com/product_show-hppe.html

其他详情(用途,包装):
HPPE is a specific nonelectrophilic and physiological Bach1 inhibitor via heme-binding sites of Bach1 protein, derepresses Bach1-mediated repression.HPPE induces up-regulation of Hmox1 mRNA is mediated by Bach1 inhibition in vivo.Nuclear export of Bach1 is required for HPPE-mediated Bach1 derepression, HPPE has an additional activity in Nrf2 stabilization besides Bach1 inhibition.Pre- and posttreatment of HPPE is neuroprotective against acute MPTP neurotoxicity.HPPE significantly reduced MPTP-induced increases in TNF-α and Mcp-1 mRNA levels, HPPE significantly increased mRNA levels of Nrf2 compared to MPTP-treated mice that received the vehicle.Bach1 is a known transcriptional repressor of the Nrf2 pathway.Bach1 ablation is cytoprotective, as it suppresses reactive oxygen species (ROS) generation, mitigates excessive inflammation, improves mitochondrial function, and inhibits apoptosis.

供应商信息:

公司名:DC Chemicals Limited 推荐

认证状态: 已认证供应商

商品数: 34963件

电话: 58447131

地址: 浦东新区金豫路100号

地区: 上海市浦东新区

联系人: Tony Cao

联系人电话: 13564518121

邮件:sales@dcchemicals.com

网址:http://www.dcchemicals.com

主要市场:

年贸易额:>1000万

外贸占销售比例:

主要合作伙伴:

公司介绍:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.

推荐生产厂家/供应商:

公司名:上海化源生化科技有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情: 化合物HPPE


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HPPE供应商

其他供应商价格:

2024-07-15 价格:需询单 化合物HPPE

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HPPE价格

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HPPE价格为$1080.0/100mg, 由HPPE生产厂家DC Chemicals Limited提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:HPPE_价格_生产厂家【DC Chemicals Limited】

标题:HPPE - 生产厂家:DC Chemicals Limited 地址:https://m.chemsrc.com/mip/chanpin/5335300.html