SKLB-03176

产品详情：

更新时间： 2024-07-17 15:06:25

CAS号：2609675-22-9

常用名： SKLB-03176

价格：
$500.0/5mg

纯度： 98.0%

备货期： 3天

库存： 3

产品页： https://www.dcchemicals.com/product_show-sklb-03176.html

其他详情（用途，包装）：
SKLB-03176 (SKLB03176) is a potent, selective, covalent EZH2 inhibitor with IC50 of 47 nM, covalently binds to the SAM pocket of EZH2.SKLB-03176 showed good inhibitory activity against mutations EZH2 Y641F, EZH2 Y641N, and EZH2A677G at 200 nM concentration.SKLB-03176 exhibited weak activity against other targets, such as 5 histone methyltransferases and more than 30 kinases, >50-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1 (IC50=2.45 uM).SKLB-03176 inhibited the activity of a variety of EZH2 mutants and significantly inhibited the expression of H3K27Me3 in cells.SKLB-03176 showed no cytotoxicity to normal cells.

供应商信息：

公司名：DC Chemicals Limited 推荐

认证状态： 已认证供应商

商品数： 34963件

电话： 58447131

地址： 浦东新区金豫路100号

地区： 上海市浦东新区

联系人： Tony Cao

联系人电话： 13564518121

邮件：sales@dcchemicals.com

网址：http://www.dcchemicals.com

主要市场：

年贸易额：>1000万

外贸占销售比例：

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公司介绍：
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.

D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.

Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.

SKLB-03176

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