AMXI-5001
产品详情：
更新时间： 2024-07-17 15:06:25
CAS号：2170491-77-5
常用名：
价格：
$需询单/100mg
$需询单/250mg
$需询单/1g
纯度： 98.0%
备货期： 3天
库存： 3
产品页： https://www.dcchemicals.com/product_show-amxi-5001.html
其他详情（用途，包装）：
AMXI-5001 (AMXI 5001) is a novel, highly potent, orally active dual PARP1/2 (IC50 5/0.05 nM) and microtubule polymerization inhibitor, inhibits intracellular PAR formation with IC50 of 7 nM.AMXI-5001 binds to the catalytic domain of human PARP1 and is a weak tankyrase inhibitor (800-fold lower than IC50 towards either PARP1 or PARP2 enzymes).AMXI-5001 inhibited tubulin polymerization in a dose-dependent manner.AMXI-5001 exhibited selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors.AMXI-5001 is highly active in both BRCA mutated and wild type cancers.AMXI-5001 elicited a remarkable In vivo preclinical anti-tumor activity in a BRCA mutated TNBC model induced complete regression of established tumors, including exceedingly large tumors, demonstrated superior anti-tumor effects compared to either single agent (PARP or microtubule) inhibitor or combination with both agents.
供应商信息：
公司名：DC Chemicals Limited 推荐
认证状态： 已认证供应商
商品数： 34963件
电话： 58447131
地址： 浦东新区金豫路100号
地区： 上海市浦东新区
联系人： Tony Cao
联系人电话： 13564518121
邮件：sales@dcchemicals.com
主要市场：
年贸易额：>1000万
外贸占销售比例：
主要合作伙伴：
公司介绍：
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
推荐生产厂家/供应商：
公司名：上海化源生化科技有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥4500.9/5mg
￥8000.9/10mg
联系人：阿拉丁
产品详情：
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其他供应商价格：
2024-07-15 价格：需询单
2025-02-05 价格：￥4500.9
查看所有价格请点击：
相关产品价格：
AMXI-5001价格为$需询单/100mg, 由AMXI-5001生产厂家DC Chemicals Limited提供，供应信息包括纯度，备货期/库存，供货能力等。>>电脑版：AMXI-5001_价格_生产厂家【DC Chemicals Limited】
标题：AMXI-5001 - 生产厂家：DC Chemicals Limited 地址：https://m.chemsrc.com/mip/chanpin/5343718.html