补骨脂酚

产品详情：

发布时间： 2024-03-06 16:07:19

CAS号：10309-37-2

常用名： 补骨脂酚

价格：
￥需询单/1g

纯度： 98.0%

备货期： 需询单

库存： 现货

产品页： https://www.scstandards.com/product/1945.html

其他详情（用途，包装）：
用途： Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L; has anti-tumor effects.IC50 value:Target:in vitro: Bakuchiol reduced mitochondrial membrane potential (Psim) of cells in a concentration- and time-dependent manner, showing a more potent effect than that of resveratrol. S phase arrest, caspase 9/3 activaton, p53 and Bax up-regulation, as well as Bcl-2 down-regulation were observed in bakuchiol-treated A549 cells [1]. UGT2B7 was inhibited by the strongest intensity. The noncompetitive inhibition was demonstrated by the results obtained from Dixon plot and Lineweaver-Burk plot. The Ki value was calculated to be 10.7 μM [2]. Bakuchiol was found to be naturally occurring potent inhibitors of hCE2, with low Ki values ranging from 0.62μM to 3.89μM [3]. After exposure to bakuchiol at 0.25-fold, 0.5-fold and 1-fold of minimum inhibitory concentration (MIC) (3.91 μg/ml) for 24h, the fungal conidia of T. mentagrophytes demonstrated a significant dose-dependent increase in membrane permeability. Moreover, bakuchiol at 1-fold MIC elicited a 187% elevation in reactive oxygen species (ROS) level in fungal cells after a 3-h incubation [4].in vivo: In combination with the reported concentration after an intravenous administration of bakuchiol (15 mg/kg) in rats, the high risk of in vivo inhibition of bakuchiol towards UGT2B7-catalyzed metabolism of drugs was indicated [2]. In a guinea pig model of tinea pedis, bakuchiol at 1%, 5% or 10% (w/w) concentration in aqueous cream could significantly reduce the fungal burden of infected feet (p 物理化学性质： CAS号：10309-37-2 常用中文名：补骨脂酚常用英文名：Bakuchiol 分子式：C18H24O 分子量：256.383 密度：1.0±0.1 g/cm3 沸点：391.4±21.0 °C at 760 mmHg 熔点：N/A 闪点：176.6±11.7 °C 储存条件：通风低温干燥

供应商信息：

公司名：成都瑞芬思德丹生物科技有限公司

认证状态： 未认证供应商

商品数： 63件

电话： 400-400099-8382

地址： 成都市温江区成都海峡两岸科技产业开发园双堰路1919号29栋

地区： 成都市温江区

联系人： 范文云

联系人电话： 18981950076

邮件：2851037746@qq.com

网址：https://www.scstandards.com/

主要市场：国内

年贸易额：1000万

外贸占销售比例：

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公司介绍：
成都瑞芬思德丹生物科技有限公司专注于：高纯度天然药物活性单体及中药对照品的研究开发；植物化学活性组份研究开发；植物有效活性部位分离定制开发；民族、民间药活性成分定制开发；天然产物工业化提取整体解决方案技术研究、并提供相应技术研究服务的国家高新技术企业。

其他供应商价格：

2022-11-29 价格：￥需询单 Bakuchiol

2025-09-17 价格：￥需询单 (S,E)-4-(3,7-二甲基-3-乙烯基辛基-1,6-二烯-1-基)苯酚

2025-12-29 价格：￥需询单补骨脂酚

2022-02-19 价格：￥836.0 补骨脂酚

2024-09-13 价格：￥需询单补骨脂酚

2019-12-26 价格：￥需询单补骨酯酚

2016-03-11 价格：￥600.0 补骨脂酚

2021-01-27 价格：￥5500.0 补骨脂酚

2024-05-21 价格：￥需询单补骨脂酚

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补骨脂酚

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