Orotic acid

产品详情：

发布时间： 2024-06-20 16:36:52

CAS号：65-86-1

常用名： 乳清酸

价格：
$需询单/1mg $需询单/100kg

纯度： 98.0%

备货期： 1天

库存： 询单

其他详情（用途，包装）：
用途： Orotic acid (OA) is an intermediate in pyrimidine metabolism.IC50 Value: Target: Nucleoside antimetabolite/analogin vitro: OA increases cell proliferation and decreases apoptosis in serum-starved SK-Hep1 hepatocellular carcinoma cells, which may ascribe to the inhibition of AMP-activated protein kinase (AMPK) phosphorylation and thus activation of mammalian target of rapamycin complex 1 (mTORC1) [1].in vivo: male Fischer 344 rats (130-150 g) to two-thirds PH in the absence or in the presence of OA (a 300-mg tablet of OA methyl ester implanted intraperitoneally at the time of two-thirds PH). treatment with OA resulted in a near-100% inhibition of RNR induced by two-thirds PH in rat liver, as monitored by enzyme activity and protein level [2]. The increases of hepatic OA and betaine levels in OA feeding rats was also found when compared to the normal rats [3]. Feeding 1% OA with diet decreased the phosphorylation of AMPK and increased the maturation of SREBP-1 and the expression of SREBP-responsive genes in the rat liver. OA-induced lipid accumulation was also completely inhibited by rapamycin. Mouse hepatocytes and mice were resistant to OA-induced lipogenesis because of little if any response in AMPK and downstream effectors [4]. 物理化学性质： CAS号：65-86-1 常用中文名：乳清酸常用英文名：Orotic acid 分子式：C5H4N2O4 分子量：156.096 密度：1.8±0.1 g/cm3 沸点：656.9±65.0 °C at 760 mmHg 熔点：>300°C 闪点：351.1±34.3 °C 储存条件：室温

供应商信息：

公司名：Taiwan Oyi peptide Co. Ltd

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其他供应商价格：

2025-02-25 价格：￥需询单乳清酸(无水)(Orotic acid)

2022-11-29 价格：￥需询单 Orotic acid (6-Carboxyuracil)

2022-02-19 价格：￥29.9 乳清酸

2016-06-27 价格：￥80.0 乳清酸

2017-08-06 价格：￥需询单乳清酸

2024-06-15 价格：￥需询单乳清酸

2018-01-09 价格：￥需询单乳清酸

2024-12-23 价格：$21.5 Orotic Acid Anhydrous

2024-05-23 价格：￥需询单乳清酸

2021-02-06 价格：￥489.0 Orotic acid

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乳清酸价格

Orotic acid

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