盐酸乙胺丁醇

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发布时间： 2024-07-15 12:30:00

CAS号：1070-11-7

常用名： 盐酸乙胺丁醇

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Ethambutol Dihydrochloride is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.Target: AntibacterialEthambutol directly affects two polymers, arabinogalactan (AG) and lipoarabinomannan (LAM) in Mycobacterium smegmatis. In M. smegmatis, Ethambutol inhibits synthesis of arabinan completely and inhibits AG synthesis most likely as a consequence of this; more than 50% of the cell arabinan is released from the bacteria following Ethambutol treatment, whereas no galactan is released. Ethambutol main targets against embB gene product in M. avium. Ethambutol induces 60% changes in the embB gene in M. tuberculosis resistant mutants [1]. Ethambutol is effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of the M. aviumcomplex (MAC) are sensitive to Ethambutol. [1] Ethambutol is potency against M. tuberculosis (H37Rv) with MIC of 0.5 μg/mL in vitro [2]. Ethambutol is efficient on treatment of mycobacterial-infected macrophages. When M. tuberculosis infected macrophages are treated with 6 μg/mL Ethambutol, the log CFUs following treatment for 3 days is 4.17, while value in control group is 4.8. The MICs for M. avium (MTCC 1723) and M. smegmatis (MTCC 6) are 15 μg/mL and 0.18 μg/mL, respectively. Ethambutol is efficient in animal model. 100 mg/kg Ethambutol given orally 15 days post i.v. infection 1 ×/week for 5 weeks, induces a lower log CFU compared with untreatment (4.59 vs 5.07) [3]. 物理化学性质： CAS号：1070-11-7 常用中文名：盐酸乙胺丁醇常用英文名：Ethambutol dihydrochloride 分子式：C10H26Cl2N2O2 分子量：277.232 密度：N/A 沸点：345.3ºC at 760 mmHg 熔点：198-200°C 闪点：113.7ºC 储存条件：Refrigerator

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公司名：上海念兴实业有限公司推荐

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其他供应商价格：

2022-02-19 价格：￥561.9 乙胺丁醇二盐酸盐

2019-03-05 价格：￥88.0 盐酸乙胺丁醇

2026-03-10 价格：￥需询单 2,2'-(1,2-乙二胺)二-1-丁醇二盐酸盐

2024-07-15 价格：需询单盐酸乙胺丁醇

2021-02-06 价格：￥889.0 Ethambutol HCl

2018-06-14 价格：￥需询单盐酸乙胺丁醇

2018-03-23 价格：￥需询单盐酸乙胺丁醇

2024-01-09 价格：$需询单 TIANFU CHEM Ethambutol dihydrochloride

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盐酸乙胺丁醇

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