盐酸依福地平一乙醇盐

产品详情：

发布时间： 2024-07-15 12:30:09

CAS号：111011-76-8

常用名： 盐酸依福地平

价格：

纯度： 99.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Efonidipine(NZ-105) Hcl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).IC50 value: Target: calcium channel blockerin vitro: Efonidipine and nifedipine, but not other examined CCBs, also increased the N(6), 2'-O-dibutyryladenosine 3',5'-cyclic monophosphate (dbcAMP)-induced StAR mRNA, which reflects the action of adrenocorticotropic hormone, and efonidipine and R(-)-efonidipine enhanced the dbcAMP-induced DHEA-S production in NCI-H295R adrenocortical carcinoma cells [1]. I(Ca(T)) was blocked mainly by a tonic manner by nifedipine, by a use-dependent manner by mibefradil, and by a combination of both manners by efonidipine. IC50s of these Ca2+ channel antagonists to I(Ca(T)) and L-type Ca2+ channel current (I(Ca(L))) were 1.2 micromol/l and 0.14 nmol/l for nifedipine; 0.87 and 1.4 micromol/l for mibefradil, and 0.35 micromol/l and 1.8 nmol/l for efonidipine, respectively [4].in vivo: Twenty hypertensive patients on chronic hemodialysis were given efonidipine 20-60 mg twice daily and amlodipine 2.5-7.5 mg once daily for 12 weeks each in a random crossover manner. The average blood pressure was comparable between the efonidipine and amlodipine periods (151 + or - 15/77 + or - 8 versus 153 + or - 15/76 + or - 8 mmHg). The pulse rate did not change significantly during the administration periods [2]. In the UM-X7.1 group, EFO treatment significantly attenuated the decrease of LVEF without affecting blood pressure compared with the vehicle group. EFO treatment decreased heart rate (by approximately 10%) in both groups [3]. 物理化学性质： CAS号：111011-76-8 常用中文名：盐酸依福地平常用英文名：Efonidipine 分子式：C36H45ClN3O8P 分子量：631.655 密度：1.3±0.1 g/cm3 沸点：746.9±60.0 °C at 760 mmHg 熔点：151° (dec) 闪点：405.5±32.9 °C 储存条件：Desiccate at +4°C

供应商信息：

公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

邮件：sales@echemcloud.com

网址：http://www.echemcloud.com

主要市场：

年贸易额：

外贸占销售比例：

主要合作伙伴：

公司介绍：

其他供应商价格：

2022-03-04 价格：￥144.9 盐酸依非替尼单乙醇酸盐

2018-07-28 价格：￥需询单依福地平 111011-76-8

2017-12-09 价格：￥需询单盐酸依福地平

2022-05-12 价格：$需询单 Efonidipine hydrochloride monoethanolate

2024-01-09 价格：$需询单 Efonidipine hydrochloride ethanolate

查看所有价格请点击：

盐酸依福地平价格

盐酸依福地平一乙醇盐

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：