酒石酸托特罗定
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发布时间: 2024-07-15 12:30:59
CAS号:124937-52-6
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纯度: 98.0%
备货期: 10天
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用途: Tolterodine Tartrate(PNU-200583E; Kabi-2234) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. IC50 Value:Target: mAChRin vitro: Carbachol-induced contractions of isolated guinea pig bladder were effectively inhibited by tolterodine (IC50 14 nM) and 5-HM (IC50 5.7 nM). The IC50 values were in the microM range and the antimuscarinic potency of tolterodine was 27, 200 and 370-485 times higher, respectively, than its potency in blocking histamine receptors, alpha-adrenoceptors and calcium channels. The active metabolite, 5-HM, was >900 times less potent at these sites than at bladder muscarinic receptors [1].in vivo: Tolterodine was extensively metabolized in vivo [2]. In the passive-avoidance test, tolterodine at 1 or 3 mg/kg had no effect on memory; the latency to cross and percentage of animals crossing were comparable to controls. In contrast, scopolamine induced a memory deficit; the latency to cross was decreased, and the number of animals crossing was increased [3]. 物理化学性质: CAS号:124937-52-6 常用中文名:酒石酸托特罗定 常用英文名:Tolterodine tartrate 分子式:C26H37NO7 分子量:475.574 密度:1.003 g/cm3 沸点:442.2ºC at 760 mmHg 熔点:205-210ºC 闪点:192.1ºC 储存条件:Store at +4°C
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公司名:上海念兴实业有限公司 推荐
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公司名:上海化源世纪贸易有限公司
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公司名:广东翁江化学试剂有限公司
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¥400.0/5g
¥1200.0/25g
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酒石酸托特罗定价格为, 由酒石酸托特罗定生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:酒石酸托特罗定_价格_生产厂家【上海念兴实业有限公司】
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