N-(4-丁基-2-甲基苯基)乙酰胺

产品详情：

发布时间： 2024-07-15 12:32:05

CAS号：143360-00-3

常用名： N1-(4-丁基-2-甲基苯基)乙酰胺

价格：

纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： SMIP004 is a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, it was found to downregulate SKP2 and to stabilize p27.IC50 Value: 1.09 uM (MTT assay in LNCaP-S14 cells) [1]Target: Apoptosis inducer; SKP2in vitro: Whereas SMIP012 and 016 were moderately toxic in normal fibroblasts, SMIPs 001 and 004 showed substantial cancer cell specificity being at least five times more potent in LNCaP-S14 than in IMR90 cells , treatment with either MG132 or SMIP004 increased p27 half-life to > 6 h [1]. Both SMIP001 and 004 led to a strong increase in the recruitment of p27 to CDK2, while SMIP001 also slightly increased coprecipitation of p21 (Figure 6c). SMIP004 also reduced the amounts of cyclins E and A retrieved with CDK2. This was paralleled by a marked downregulation of cyclins E and A upon SMIP004 treatment. SMIP004 decreased the levels of positive cell cycle regulators, upregulated cyclin-dependent kinase inhibitors, and resulted in G1 arrest, inhibition of colony formation in soft agar, and cell death [2].in vivo: SMIP004 potently inhibits the growth of prostate and breast cancer xenografts in mice [2].Clinical trial: 物理化学性质： CAS号：143360-00-3 常用中文名：N1-(4-丁基-2-甲基苯基)乙酰胺常用英文名：SMIP004 分子式：C13H19NO 分子量：205.29600 密度：1.003g/cm3 沸点：343ºC at 760mmHg 熔点：N/A 闪点：206.1ºC 储存条件：2-8℃

供应商信息：

公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

邮件：sales@echemcloud.com

网址：http://www.echemcloud.com

主要市场：

年贸易额：

外贸占销售比例：

主要合作伙伴：

公司介绍：

其他供应商价格：

2022-03-04 价格：￥1235.0 SMIP004

2024-07-15 价格：需询单 N-(4-丁基-2-甲基苯基)乙酰胺

2020-12-08 价格：￥1809.0 SMIP004

查看所有价格请点击：

N1-(4-丁基-2-甲基苯基)乙酰胺价格

N-(4-丁基-2-甲基苯基)乙酰胺

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：