马来酸阿莫曲坦
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更新时间: 2026-01-01 11:23:31
CAS号:181183-52-8
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纯度: 98.0%
备货期: 10天
库存: 现货
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用途: Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine.IC50:Target: 5-hydroxytryptamine1B/1D (5-HT1B/1D) ReceptorAlmotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors in several species, including the human, while affinity for 5-HT receptors other than 5-HT(1B/1D) was clearly less. Almotriptan did not exhibit significant affinity for several non-5-HT receptors studied up to 100 microM. Almotriptan inhibited forskolin-stimulated cyclic AMP accumulation in HeLa cells transfected with 5-HT(1B) or 5-HT(1D) human receptors [1]. Almotriptan had a mild antiemetic effect and a slight, transient diuretic effect in dogs, although the latter effect is probably of no clinical relevance. In addition, no effect on the respiratory system of conscious guinea pigs was observed following almotriptan treatment. These results indicate that almotriptan has a favourable safety profile with respect to the central nervous, renal and respiratory systems [2]. 物理化学性质: CAS号:181183-52-8 常用中文名:依来曲普坦 常用英文名:Almotriptan 分子式:C21H31N3O7S 分子量:469.552 密度:1.27g/cm3 沸点:538.7ºC at 760mmHg 熔点:170-172ºC 闪点:279.6ºC 储存条件:-20°C Freezer
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马来酸阿莫曲坦价格为, 由马来酸阿莫曲坦生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:马来酸阿莫曲坦_价格_生产厂家【上海念兴实业有限公司】
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