2-巯基乙磺酸钠

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发布时间： 2024-07-15 12:33:21

CAS号：19767-45-4

常用名： 美司那

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： 2-mercaptoethane sulfonate (Mesna), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide.IC50 Value: 182 mM (decreased superoxide anion production stimulated with PMA (tetradecanoylphorbol acetate) in PMN in-vitro); 70mM (inhibited H2O2 production) [3]Target: in vitro: MESNA had no effect on the qualitative and quantitative characteristics of the indicated processes in both the types of the doxorubicin sensitive cells. The combined use of doxorubicin and phosphamide or cyclophosphane the use of MESNA for lowering the urotoxic action of oxazophosphorines had no effect on the biological efficacy of doxorubicin [4].in vivo: AMH-positive follicles were significantly decreased after cisplatin administration, which was significantly reversed when mesna was co-administered with cisplatin. The end product of lipid peroxidation, malondialdehyde (MDA), was significantly increased, but the anti-oxidative enzymatic activity of superoxide dismutase (SOD) and glutathione (GSH) were significantly decreased in cisplatin groups when compared with NS group. In contrast, after co-administration of cisplatin with mesna, MDA was significantly decreased whereas the activity of SOD and the concentration of GSH were increased. Moreover, mesna did not decrease the anti-tumor property of cisplatin in HePG2 cell lines [2]. After head trauma, tissue malondialdehyde levels increased; these levels were significantly decreased by MESNA administration. Caspase-3 levels were increased after trauma, but no effect of MESNA was determined in caspase-3 activity [1].Clinical trial: Effects of Mesna on Homocysteine in Kidney Failure . Phase2 物理化学性质： CAS号：19767-45-4 常用中文名：美司那常用英文名：MESNA 分子式：C2H5NaO3S2 分子量：164.179 密度：N/A 沸点：N/A 熔点：>240°C dec. 闪点：N/A 储存条件：-20?C Freezer, Under Inert Atmosphere

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公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

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其他供应商价格：

2022-02-19 价格：￥1047.9 2-巯基乙烷磺酸钠

2019-03-05 价格：￥478.0 2-巯基乙烷磺酸钠

2026-03-10 价格：￥需询单美司那

2024-08-06 价格：￥15200.0 2-巯乙基磺酸钠

2024-07-15 价格：需询单 2-巯基乙磺酸钠

2021-05-10 价格：￥需询单美司那

2017-08-08 价格：￥需询单美司那

2017-12-29 价格：￥需询单美司那

2017-09-13 价格：￥需询单美司那

2021-02-06 价格：￥789.0 Mesna

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美司那价格

2-巯基乙磺酸钠

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