澳洲茄边碱

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更新时间： 2025-12-28 17:52:01

CAS号：20311-51-7

常用名： 澳洲茄边碱

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells. IC50 value:Target: Anticancer natural compoundin vitro: Solamargine reduced HepG2 cell viability in a concentration-dependent manner. At 7.5μM solamargine decreased cell viability by less than 20% in HepG2 cells. At the highest dose, solamargine decreased cell migration and invasion by more than 70% and 72% in HepG2 cells, respectively. Western blotting and gelatin zymography results showed that solamargine reduced expression and function of MMP-2 and MMP-9 proteins [1]. SM increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) in a time-dependent fashion. SM also inhibited phosphorylation and protein expression of signal transducer and activator of transcription 3 (Stat3), a transcription factor, which was abrogated by the SB203580, a specific inhibitor of p38 MAPK. In addition, SM induced protein expression of p21, one of cyclin-dependent kinase inhibitors, and this was not observed in cell overexpression of Stat3 or cells treated with SB203580 [2]. SM significantly inhibited the growth of SMMC-7721 and HepG2 cells and induced cell apoptosis. Cell cycle analysis revealed that SM caused cell cycle arrest at the G2/M phase. Moreover, SM could up-regulate the expression of caspase-3 [3]. 物理化学性质： CAS号：20311-51-7 常用中文名：澳洲茄边碱常用英文名：Solamargine 分子式：C45H73NO15 分子量：868.059 密度：1.4±0.1 g/cm3 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C

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公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

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2024-09-29 价格：￥需询单澳洲茄边碱

2024-03-12 价格：￥5149.9 澳洲茄边碱

2025-12-29 价格：￥需询单澳洲茄边碱

2024-07-15 价格：需询单澳洲茄边碱

2019-03-05 价格：￥938.0 澳洲茄边碱

2016-03-11 价格：￥950.0 澳洲茄边碱

2021-06-07 价格：￥需询单澳洲茄边碱

2024-03-04 价格：￥350.0 澳洲茄边碱

2021-02-06 价格：￥2489.0 Solamargine

2024-05-08 价格：￥需询单澳洲茄边碱

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