Miglustat盐酸盐

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更新时间： 2025-12-30 10:09:42

CAS号：210110-90-0

常用名： Miglustat盐酸盐

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).Target: OthersMiglustat is an inhibitor of the ceramide-specific glycosyltransferase, which catalyzes the first step of glycosphingolipid biosynthesis and is currently approved for the oral treatment of type 1 GD [1]. Consumption of a standard high-fat breakfast within 30 minutes before administration of miglustat significantly reduced peak exposure but did not significantly affect the extent of systemic exposure to miglustat. The peak plasma concentration (C(max)) decreased by 36% on average following administration with food. Area under the plasma concentration-time curve (AUC(0-infinity)) showed a modest (14%) decrease with food, but the 90% confidence interval was within the acceptance limit of 80% to 125%. The median (min-max) time to C(max) (t(max)) was prolonged from 2.5 (1.0-4.0) hours in the fasted state to 4.5 (1.5-8.0) hours in the fed state, whereas the apparent terminal half-life was approximately 8 hours and not affected by food [2]. 物理化学性质： CAS号：210110-90-0 常用中文名：Miglustat盐酸盐常用英文名：Miglustat hydrochloride 分子式：C10H22ClNO4 分子量：255.739 密度：N/A 沸点：421.2ºC at 760 mmHg 熔点：169-172ºC 闪点：208.5ºC 储存条件：2-8℃

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2022-03-04 价格：￥537.9 Miglustat hydrochloride

2022-05-12 价格：$需询单 Miglustat hydrochloride(N-Butyldeoxynojirimycin, Hydrochloride)

2021-02-06 价格：￥1309.0 Miglustat hydrochloride

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Miglustat盐酸盐价格

Miglustat盐酸盐

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