去甲氧基姜黄素

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发布时间： 2024-07-15 12:33:54

CAS号：22608-11-3

常用名： 去甲氧基姜黄素

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纯度： 93.5%

备货期： 10天

库存： 现货

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用途： Demethoxycurcumin(Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.IC50 value: Target:in vitro: DMC significantly decreased NO secretion by 35-41% in our inflamed cell model. Decrease in NO production by DMC was concomitant with down-regulation of iNOS at mRNA and protein levels compared to proinflammatory cytokine cocktail and LPS-treated controls. Mechanism of action of DMC may be partly due to its potent inhibition of the iNOS pathway [1]. BDMCCN has the strongest inhibitory activity toward BACE-1 with 17 μM IC50, which was 20 and 13 times lower than those of CCN and DMCCN respectively [2]. Genes associated with DNA damage and repair, cell-cycle check point and apoptosis could be altered by DMC; in particular, 144 genes were found up-regulated and 179 genes down-regulated in NCI-H460 cells after exposure to DMC [3]. in vivo: At low doses, both the curcuminoid mixture and curcumin I did not affect brain stimulation reward, whereas, higher doses increased ICSS thresholds. Curcumin II and curcumin III did not affect brain stimulation reward at any doses. Subthreshold doses of the curcuminoid mixture and curcumin I inhibited the reward-facilitating effect of morphine. 物理化学性质： CAS号：22608-11-3 常用中文名：去甲氧基姜黄素常用英文名：demethoxycurcumin 分子式：C20H18O5 分子量：338.354 密度：1.3±0.1 g/cm3 沸点：571.4±50.0 °C at 760 mmHg 熔点：168ºC 闪点：205.5±23.6 °C 储存条件：2-8°C

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公司名：上海念兴实业有限公司推荐

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2024-07-15 价格：需询单去甲氧基姜黄素

2019-03-05 价格：￥1588.0 去甲氧基姜黄素

2021-04-03 价格：￥3850.0 Demethoxycurcumin

2025-09-17 价格：￥需询单去甲氧基姜黄素

2024-03-12 价格：￥199.9 脱甲氧基姜黄素

2017-07-05 价格：￥需询单去甲氧基姜黄素

2023-11-02 价格：￥300.0 去甲氧基姜黄素

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