Mianserin
产品详情:
发布时间: 2024-07-15 12:34:07
CAS号:24219-97-4
常用名:
价格:
纯度: 98.0%
备货期: 10天
库存: 现货
其他详情(用途,包装):
用途: Mianserin is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.Target: H1 receptorMianserin is a psychoactive drug of the tetracyclic antidepressant (TeCA) therapeutic family. It is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic (anti-anxiety), hypnotic (sedating), antiemetic (nausea and vomiting-attenuating), orexigenic (appetite-stimulating), and antihistamine effects. It is not approved for use in the US, but its analogue, mirtazapine, is. Mianserin was the first antidepressant to reach the UK market that was less dangerous than the tricyclic antidepressants in overdose.Mianserin is an antagonist/inverse agonist of the H1, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1-adrenergic, and α2-adrenergic receptors, and also inhibits the reuptake of norepinephrine. As a high affinity H1 receptor inverse agonist, mianserin has strong antihistamine effects (sedation, weight gain, etc.). Contrarily, it has negligible affinity for the mACh receptors, and thus lacks any anticholinergic properties. It was recently found to be a potent kappa opioid receptor agonist. In addition, mianserin also appears to be a potent antagonist of the neuronal octopamine receptor. What implications this may have on mood are currently unknown, however octopamine has been implicated in the regulation of sleep, appetite and insulin production and therefore may theoretically contribute to the overall side effect profile of mianserin. 物理化学性质: CAS号:24219-97-4 常用中文名:米安舍林 常用英文名:Mianserin 分子式:C18H20N2 分子量:264.36500 密度:1.18g/cm3 沸点:411.3ºC at 760mmHg 熔点:N/A 闪点:186.1ºC 储存条件:2-8℃
供应商信息:
公司名:上海念兴实业有限公司 推荐
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地址: 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市普陀区
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2021-02-06 价格:¥1915.0
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Mianserin价格为, 由Mianserin生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:Mianserin_价格_生产厂家【上海念兴实业有限公司】
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