补骨脂查尔酮

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发布时间： 2024-07-15 12:34:26

CAS号：28448-85-3

常用名： 补骨脂查耳酮

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纯度： 98.0%

备货期： 10天

库存： 现货

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用途： Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L.; has been widely used as traditional Chinese medicine; antibiotic or anticancer agent.IC50 value:Target:Bavachalcone inhibited osteoclast formation from precursor cells with the IC(50) of approximately 1.5 microg ml(-1). The activation of MEK, ERK, and Akt by receptor activator of nuclear factor kappaB ligand (RANKL), the osteoclast differentiation factor, was prominently reduced in the presence of bavachalcone. The induction of c-Fos and NFATc1, key transcription factors for osteoclastogenesis, by RANKL was also suppressed by bavachalcone [1]. Bavachalcone exhibited a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro [2]. Bavachalcone had stronger inhibition on UGT1A1 and UGT1A7 than corylin which did not inhibit UGT1A1, UGT1A3, UGT1A7, UGT1A8, UGT1A10, and UGT2B4. Data fitting using Dixon and Lineweaver-Burk plots demonstrated the noncompetitive inhibition of bavachalcone against UGT1A1 and UGT1A7-mediated 4-MU glucuronidation reaction. The values of inhibition kinetic parameters (Ki) were 5.41 μ M and 4.51μ M for UGT1A1 and UGT1A7, respectively [3]. 物理化学性质： CAS号：28448-85-3 常用中文名：补骨脂查耳酮常用英文名：Bavachalcone 分子式：C20H20O4 分子量：324.370 密度：1.2±0.1 g/cm3 沸点：549.6±50.0 °C at 760 mmHg 熔点：168-169℃ 闪点：300.2±26.6 °C 储存条件：-20°C

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2024-09-29 价格：￥需询单 Broussochalcone B

2025-02-05 价格：￥2080.9 补骨脂查耳酮

2025-12-29 价格：￥需询单补骨脂查尔酮

2024-07-15 价格：需询单补骨脂查尔酮

2019-03-05 价格：￥638.0 补骨脂查尔酮

2016-10-29 价格：￥650.0 补骨脂查耳酮

2022-02-17 价格：￥1120.0 补骨脂查尔酮

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补骨脂查尔酮

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