多沙普仑

产品详情：

发布时间： 2024-07-15 12:34:35

CAS号：309-29-5

常用名： 多沙普仑

价格：

纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.Target: Potassium ChannelDoxapram is a respiratory stimulant. Doxapram (15-150 microM) also evoked 3H overflow in a concentration dependent manner, and doxapram-evoked release was inhibited by the Ca2+ channel blocker nifedipine (5 microM). Analysis of released tritiated compounds suggested that doxapram preferentially stimulated the release of dopamine. Our results indicate that the mechanism of action of doxapram shares similarities with that of hypoxia in the carotid body [1]. Doxapram (1-100 microM) caused rapid, reversible and dose-dependent inhibitions of K+ currents recorded in type I cells (IC50 approximately 13 microM). doxapram was also seen to directly inhibit Ca(2+)-independent K+ currents. Doxapram was a more potent inhibitor of the Ca(2+)-activated K+ currents recorded under control conditions. Doxapram (10 microM) was without effect on L-type Ca2+ channel currents recorded under conditions where K+ channel activity was minimized and was also without significant effect on K+ currents recorded in the neuronal cell line NG-108 15, suggesting a selective effect on carotid body type I cells. The effects of doxapram on type I cells show similarities to those of the physiological stimuli of the carotid body, suggesting that doxapram may share a similar mechanism of action in stimulating the intact organ [2]. 物理化学性质： CAS号：309-29-5 常用中文名：多沙普仑常用英文名：Doxapram 分子式：C24H30N2O2 分子量：378.507 密度：1.1±0.1 g/cm3 沸点：536.4±50.0 °C at 760 mmHg 熔点：N/A 闪点：278.2±30.1 °C 储存条件：-20℃

供应商信息：

公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

邮件：sales@echemcloud.com

网址：http://www.echemcloud.com

主要市场：

年贸易额：

外贸占销售比例：

主要合作伙伴：

公司介绍：

其他供应商价格：

2022-03-04 价格：￥2059.9 多沙普仑

2024-07-15 价格：需询单多沙普仑

2021-02-06 价格：￥2756.0 Doxapram

2017-06-30 价格：￥需询单 Doxapram

2024-01-09 价格：$需询单 Doxapram

查看所有价格请点击：

多沙普仑价格

多沙普仑

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：