氨茶碱

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发布时间： 2024-07-15 12:34:39

CAS号：317-34-0

常用名： 氨茶碱

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD.Target: PhosphodiesteraseAminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD. It is used off-label as a reversal agent during nuclear stress testing. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor.Adenosine is an endogenous extracellular messenger that can regulate myocardial oxygen needs. It acts through cellular surface receptors which effect intracellular signalling pathways to increase coronary artery blood flow, slow heart rate, block atrioventricular node conduction, suppress cardiac automaticity, and decrease β-adrenergic effects on contractility. Adenosine also antagonizes chronotropic and ionotropic effects of circulating catecholamines. Overall, adenosine decreases the heart's rate and force of contraction, which increases blood supply to the cardiac muscle. Given specific circumstances this mechanism (which is intended to protect the heart) may cause atropine-resistant refractory bradyasystole. Adenosine's effects are concentration-dependent. Adenosine's receptors are competitively antagonized by methylxanthines such as aminophylline. Aminophylline competitively antagonizes the cardiac actions of adenosine at the cell surface receptors. Thus, it increases heart rate and contractility. 物理化学性质： CAS号：317-34-0 常用中文名：氨茶碱常用英文名：Aminophylline 分子式：C16H24N10O4 分子量：420.426 密度：N/A 沸点：454.1ºC at 760mmHg 熔点：269-270 °C 闪点：N/A 储存条件：−20°C

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公司名：上海念兴实业有限公司推荐

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2022-02-19 价格：￥294.9 氨茶碱

2024-07-10 价格：￥288.0 氨茶碱

2016-11-05 价格：￥100.0 氨茶碱

2024-05-17 价格：￥需询单氨茶碱

2021-02-06 价格：￥909.0 Aminophylline

2017-08-08 价格：￥需询单氨茶碱

2022-05-25 价格：￥100.0 氨茶碱

2023-09-06 价格：￥145.0 氨茶碱

2024-01-20 价格：￥90.0 氨茶碱

2024-01-09 价格：$需询单 Aminophylline

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