甲硫米特

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发布时间： 2024-07-15 12:34:51

CAS号：34839-70-8

常用名： 甲硫米特

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.IC50 Value: 0.92 uM (Ki with glycolaldehyde as the varied substrate for E3)Target: H2 receptorMetiamide is an intermediate compound in the development of the successful anti-ulcer drug cimetidine. in vitro: Metiamide is a competitive with aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex withK i values of 0.92 μM glycolaldehyde as the varied substrate[1]. Data was got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM)[2]. in vivo: Metiamide is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. Metiamide inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Metiamide include an increase in gastric bacterial flora such as nitrate-reducing organisms. 物理化学性质： CAS号：34839-70-8 常用中文名：甲硫米特常用英文名：Metiamide 分子式：C9H16N4S2 分子量：244.380 密度：1.2±0.1 g/cm3 沸点：463.0±55.0 °C at 760 mmHg 熔点：N/A 闪点：233.8±31.5 °C 储存条件：2-8℃

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公司名：上海念兴实业有限公司推荐

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2022-03-04 价格：￥1571.0 Metiamide

2024-07-15 价格：需询单甲硫米特

2023-11-18 价格：￥需询单 Metiamide

2021-02-06 价格：￥1748.0 Metiamide

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甲硫米特

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