JDTic?

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发布时间： 2024-07-15 12:34:57

CAS号：361444-66-8

常用名： JDTic

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纯度： 98.0%

备货期： 10天

库存： 现货

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用途： JDTic is a highly selective antagonist for the κ-opioid receptor; without affecting the μ- or δ-opioid receptors. IC50 value:Target: κ-opioid receptorJDTic is a 4-phenylpiperidine derivative, distantly structurally related to analgesic drugs such as meperidine and ketobemidone, and more closely to the mu opioid antagonist alvimopan, and is structurally distinct from other kappa antagonists such as norbinaltorphimine. JDTic has a very long duration of action, with effects in animals seen for up to several weeks after administration of a single dose, although its binding to the kappa opioid receptor is not irreversible and its long-acting effects are instead caused by altered activity of c-Jun N-terminal kinases. Animal studies suggest that it may produce antidepressant and anxiolytic effects, as well as having possible application in the treatment of addiction to cocaine and morphine. 物理化学性质： CAS号：361444-66-8 常用中文名：JDTic 常用英文名：JDTic 分子式：C28H39N3O3 分子量：465.628 密度：1.1±0.1 g/cm3 沸点：701.9±60.0 °C at 760 mmHg 熔点：N/A 闪点：378.3±32.9 °C 储存条件：2-8℃

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2022-03-04 价格：￥1258.0 JDTic

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