Azatadine?

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发布时间： 2024-07-15 12:35:07

CAS号：3964-81-6

常用名： 6,11-二氢-11-(1-甲基-4-哌啶亚基)-5H-苯并[5,6]环庚烷并[1,2-b]吡啶

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.Target: Histamine ReceptorAzatadine, a new antihistamine, was evaluated for its efficacy in 20 patients with chronic allergic rhinitis. Eighty percent of patients had symptomatic relief with a twice daily dosage of 2 mg. Sedation was volunteered as a side effect by six of the patients and was admitted by two further patients after specific questioning. A choice reaction time test gave slowing of motor function in these sedated patients. Four of the previously sedated patients experienced good symptomatic control with minimal sedation when the azatadine dose was reduced to 1 mg twice daily; slowing of motor function was not observed at this, the normal recommended dose.Azatadine delays the onset of dyspnea-induced by aerosolized histamine, acetylcholine and serotonin in the conscious guinea-pig with PD50 of 0.01 mg/kg, 0.739 mg/kg and 0.86 mg/kg. Azatadine protects conscious guinea-pigs against death induced by the intravenous injection of histamine with oral PD50 of 0.009 mg/kg in guinea-pig and 0.22 mg/kg in mice. 物理化学性质： CAS号：3964-81-6 常用中文名：6,11-二氢-11-(1-甲基-4-哌啶亚基)-5H-苯并[5,6]环庚烷并[1,2-b]吡啶常用英文名：Azatadine 分子式：C20H22N2 分子量：290.40 密度：1.127 g/cm3 沸点：450.1ºC at 760 mmHg 熔点：124-126ºC 闪点：226ºC 储存条件：2-8℃

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2024-07-15 价格：需询单 Azatadine?

2022-03-04 价格：￥2011.0 阿扎他定马来酸盐

2021-02-06 价格：￥649.0 Azatadine

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6,11-二氢-11-(1-甲基-4-哌啶亚基)-5H-苯并[5,6]环庚烷并[1,2-b]吡啶价格

Azatadine?

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