HQ-415
产品详情:
更新时间: 2026-01-11 21:29:46
CAS号:430462-93-4
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纯度: 95.0%
备货期: 10天
库存: 现货
其他详情(用途,包装):
用途: HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting a EC50 for HQ-415 is 15 μM. IC50 value: 15 μM (EC50)in vitro: In TDP-43-expressing cells, CQ fails to synergize with HQ-161 and actually antagonizes HQ-161 rescuing activity. In contrast, despite the fact that CQ was completely inactive against TDP-43, it strongly synergized with HQ-415, decreasing the EC50 from 16 to 5 μM. HQ-415 is active in the TDP-43 model, but CQ was not HQ-161 and HQ-415 are retested in dose for their ability to rescue TDP-43. Both HQ-161 and HQ-415 rescue TDP-43 toxicity. In cells expressing α-syn, HQ-161, despite being inactive on its own, synergized with HQ-415, reducing the EC50 from 21 to 14 μM. HQ-415 strongly synergizes with CQ at multiple concentrations in cells expressing α-syn. 物理化学性质: CAS号:430462-93-4 常用中文名:HQ-415 常用英文名:HQ-415 分子式:C25H25N3O3 分子量:415.484 密度:1.2±0.1 g/cm3 沸点:614.9±55.0 °C at 760 mmHg 熔点:N/A 闪点:325.7±31.5 °C 储存条件:2-8℃
供应商信息:
公司名:上海念兴实业有限公司 推荐
认证状态: 已认证供应商
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电话: 18916513247
地址: 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市普陀区
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2024-07-15 价格:需询单
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HQ-415价格为, 由HQ-415生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:HQ-415_价格_生产厂家【上海念兴实业有限公司】
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