莪术醇
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发布时间: 2024-07-15 12:35:26
CAS号:4871-97-0
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纯度: 99.0%
备货期: 10天
库存: 现货
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用途: Curcumol is a sesquiterpene originally isolated from curcuma rhizomes; shows anticancer activities both in vitro and in vivo.IC50 value:Target: Anticancer natural compoundin vitro: Curcumol exhibited time- and concentration-dependent anti-proliferative effects in SPC-A-1 human lung adenocarcinoma cells with cell cycle arrest in the G0/G1 phase while apoptosis-induction was also confirmed with flow cytometry and morphological analyses [1]. Curcumol-induced growth inhibition correlated with apoptosis induction as evidenced by Annexin V staining, and cleavage of caspase-3 and poly (ADP-ribose) polymerase (PARP) in HSC-T6. Suppression of the NF-κB translocation via inhibition of IκB-α phosphorylation by the curcumol led to the inhibition of expression of NF-κB-regulated gene, e.g. Bcl-xL and Bcl-2, in a PI3K-dependent manner, which is upstream of NF-κB activation [2]. Curcumol exhibits an inhibitory effect on receptor activator of nuclear factor kappaB ligand (RANKL)-induced osteoclast differentiation with both bone marrow-derived macrophages and RAW264.7 cells in a dose-dependent manner [3].in vivo: Anti-neoplastic effects of curcumol were also confirmed in tumor bearing mice. Curcumol (60 mg/kg daily) significantly reduced tumor size without causing notable toxicity [1]. 物理化学性质: CAS号:4871-97-0 常用中文名:莪术醇; 姜黄醇 常用英文名:Curcumol 分子式:C15H24O2 分子量:236.350 密度:1.1±0.1 g/cm3 沸点:334.5±42.0 °C at 760 mmHg 熔点:141-142ºC 闪点:134.7±22.1 °C 储存条件:室温
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公司名:上海念兴实业有限公司 推荐
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公司名:云南西力生物技术股份有限公司
区域:昆明市盘龙区
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公司名:上海阿拉丁生化科技股份有限公司
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莪术醇价格为, 由莪术醇生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:莪术醇_价格_生产厂家【上海念兴实业有限公司】
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