5-羟基-4,7-二甲氧基黄酮
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发布时间: 2024-07-15 12:35:32
CAS号:5128-44-9
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纯度: 98.0%
备货期: 10天
库存: 现货
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用途: The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines.And it also showed inhibition of the drug efflux pumps (with IC50 = 51.64 μg/ml).IC50:51.64 μg/ml(Candida albicans drug efflux pumps)[2]In vitro: The isolated 7,4'-Di-O-methylapigenin was further investigated for its inhibitory activity on ABC drug efflux pumps in C. albicans by monitoring an increase in ciprofloxacin, assessing the level of its accumulation, in response to reserpine. There was a higher accumulation of ciprofloxacin in Candida cells in the presence of 7,4'-Di-O-methylapigenin than with reserpine. The compound 7,4'-Di-O-methylapigenine demonstrated the activity in a dose-dependent manner with IC50 value of 51.64 μg/ml. These results support those obtained from synergism assays where by the underlying synergistic antifungal mechanisms could be due to blockage of ABC efflux pumps and increasing the susceptibility of Candida to miconazole.[2]In vivo: In searching for natural products as potential anti-inflammatory agents, 7,4'-Di-O-methylapigenin wasn't evaluated in vivo for its ability to inhibit acute inflammation.[1] 物理化学性质: CAS号:5128-44-9 常用中文名:5-羟基-4’,7-二甲氧基黄酮 常用英文名:7,4'-Di-O-methylapigenin 分子式:C17H14O5 分子量:298.290 密度:1.3±0.1 g/cm3 沸点:515.2±50.0 °C at 760 mmHg 熔点:N/A 闪点:193.3±23.6 °C 储存条件:-20℃
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5-羟基-4,7-二甲氧基黄酮价格为, 由5-羟基-4,7-二甲氧基黄酮生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:5-羟基-4,7-二甲氧基黄酮_价格_生产厂家【上海念兴实业有限公司】
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