TiclopidineHCl

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发布时间： 2024-07-15 12:35:40

CAS号：53885-35-1

常用名： 盐酸噻氯匹定

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.Target: Adenosine diphosphate (ADP)Ticlopidine (trade name Ticlid) is an antiplatelet drug in the thienopyridine family. Ticlopidine hydrochloride inhibits platelet aggregation with IC50 of ~2 μM in men. Like clopidogrel, it is an adenosine diphosphate (ADP) receptor inhibitor. It is used in patients in whom aspirin is not tolerated, or in whom dual antiplatelet therapy is desirable. Because it has been reported to increase the risk of thrombotic thrombocytopenic purpura (TTP) and neutropenia, its use has largely been supplanted by the newer drug, clopidogrel, which is felt to have a much lower hematologic risk. Its niche role as an alternative in those patients who do not tolerate Clopidogrel has now been superdeded by Ticagrelor and Prasugrel. The usual dose is 250 mg twice daily by the oral route.Ticlopidine hydrochloride, when orally administered to rats, results in activation of basal and prostaglandin E1 (PGE1)-stimulated adenylate cylase activity through increase in affinity of the cyclase in platelet membrane to PGE1, although it failed to affect adenosine- or sodium fluoride-stimulated activity of the enzyme. 物理化学性质： CAS号：53885-35-1 常用中文名：盐酸噻氯匹定常用英文名：Ticlopidine Hydrochloride 分子式：C14H15Cl2NS 分子量：300.247 密度：N/A 沸点：367.3ºC at 760 mmHg 熔点：205°C 闪点：175.9ºC 储存条件：库房通风低温干燥

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公司名：上海念兴实业有限公司推荐

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2022-02-19 价格：￥160.9 噻氯匹定盐酸盐

2022-11-03 价格：￥1360.0 盐酸噻氯匹定

2021-02-06 价格：￥849.0 Ticlopidine HCl

2018-03-22 价格：￥需询单盐酸噻氯匹定

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盐酸噻氯匹定价格

TiclopidineHCl

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