氟伏沙明

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发布时间： 2024-07-15 12:35:43

CAS号：54739-18-3

常用名： 氟伏沙明

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.Target: SSRIsFluvoxamine is effective in inhibiting 5-ht uptake by blood platelets and brain synaptosomes. The antagonism by fluvoxamine of the reserpine-induced lowering of the pentamethylenetetrazole convulsive threshold can be regarded as due to an effect upon 5-HT uptake. In contrast to the effects of desmethylimipramine and imipramine, no stimulatory effects are found in rats when rapidly acting reserpine-like compounds are given following a dose of fluvoxamine [1]. fluvoxamine appears to improve combat-related PTSD symptoms but not depressive symptoms. The high attrition rate and lack of a placebo group limits the conclusions of our study. Controlled studies of fluvoxamine in the treatment of PTSD are warranted [2]. Fluvoxamine was less potent at decreasing ethanol self-administration when food was available concurrently versus when ethanol was available in isolation [ED50: 4.0 (2.7-5.9) and 5.1 (4.3-6.0)]. Effects on food were similar under each condition in which food was available. The results demonstrate that the potency of fluvoxamine in reducing ethanol-maintained behavior depends on whether ethanol is available in isolation or in the context of concurrently scheduled food reinforcement [3].Clinical indications: Depression; Obsessive compulsive disorder; Social phobia FDA Approved Date: December 5, 1994Toxicity: Anorexia, Constipation, Dry mouth, Headache, Nausea, Nervousness, Skin rash, Sleep problems, Somnolence, Liver toxicity, Mania, Increase urination, Seizures, Sweating increase, Tremors, or Tourette's syndrome. 物理化学性质： CAS号：54739-18-3 常用中文名：氟伏沙明常用英文名：Fluvoxamine 分子式：C15H21F3N2O2 分子量：318.335 密度：1.2±0.1 g/cm3 沸点：370.6±52.0 °C at 760 mmHg 熔点：120-122.5ºC 闪点：177.9±30.7 °C 储存条件：-20°C Freezer, Under Inert Atmosphere

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2022-03-04 价格：￥1489.9 氟伏沙明

2025-09-17 价格：￥需询单氟伏沙明

2024-07-15 价格：需询单氟伏沙明

2024-05-10 价格：￥需询单马来酸氟伏沙明

2021-02-06 价格：￥489.0 Fluvoxamine

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