马来酸氟伏沙明
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发布时间: 2024-07-15 12:36:02
CAS号:61718-82-9
常用名:
价格:
纯度: 99.0%
备货期: 10天
库存: 现货
其他详情(用途,包装):
用途: Fluvoxamine maleate is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.Target: SSRIsFluvoxamine (maleate) is the maleate salt form of fluvoxamine, which is effective in inhibiting 5-HT uptake by blood platelets and brain synaptosomes. The antagonism by fluvoxamine of the reserpine-induced lowering of the pentamethylenetetrazole convulsive threshold can be regarded as due to an effect upon 5-HT uptake. In contrast to the effects of desmethylimipramine and imipramine, no stimulatory effects are found in rats when rapidly acting reserpine-like compounds are given following a dose of fluvoxamine [1]. fluvoxamine appears to improve combat-related PTSD symptoms but not depressive symptoms. The high attrition rate and lack of a placebo group limits the conclusions of our study. Controlled studies of fluvoxamine in the treatment of PTSD are warranted [2]. Fluvoxamine was less potent at decreasing ethanol self-administration when food was available concurrently versus when ethanol was available in isolation [ED50: 4.0 (2.7-5.9) and 5.1 (4.3-6.0)]. Effects on food were similar under each condition in which food was available. The results demonstrate that the potency of fluvoxamine in reducing ethanol-maintained behavior depends on whether ethanol is available in isolation or in the context of concurrently scheduled food reinforcement [3].Clinical indications: Depression; Obsessive compulsive disorder; Social phobia " FDA Approved Date: December 5, 1994Toxicity: Anorexia, Constipation, Dry mouth, Headache, Nausea, Nervousness, Skin rash, Sleep problems, Somnolence, Liver toxicity, Mania, Increase urination, Seizures, Sweating increase, Tremors, or Tourette's syndrome. 物理化学性质: CAS号:61718-82-9 常用中文名:马来酸氟伏沙明 常用英文名:Fluvoxamine maleat 分子式:C19H25F3N2O6 分子量:434.407 密度:N/A 沸点:370.6ºC at 760 mmHg 熔点:120-121.5ºC 闪点:177.9ºC 储存条件:2-8°C
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公司名:上海念兴实业有限公司 推荐
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公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
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¥90.9/1g
¥47.9/250mg
¥897.9/25g
¥274.9/5g
联系人:阿拉丁
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公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
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¥118.0/1g
¥348.0/5g
联系人:刘佳
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公司名:上海化源世纪贸易有限公司
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2019-03-05 价格:¥118.0
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