苯妥英钠
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更新时间: 2026-03-26 05:35:43
CAS号:630-93-3
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纯度: 98.0%
备货期: 10天
库存: 现货
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用途: Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer.Target: Sodium ChannelPhenytoin sodium is an antiepileptic drug. It is useful to treat partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels [1]. Phenytoin has low affinity for resting sodium channels at hyperpolarized membrane potentials [2]. When neurons are depolarized and the channels transition into the open and inactivated states, greater binding and block occur. The inhibitory potency is strongly use dependent, so that block accumulates with prolonged or repetitive activation, such as occurs during a seizure discharge. The blocking of sodium channels by phenytoin is of slow onset. The time course of fast sodium currents is therefore not altered in the presence of the drug and action potentials evoked by synaptic depolarizations of ordinary duration are not blocked. Thus phenytoin is able to selectively inhibit pathological hyperexcitability in epilepsy without unduly impairing ongoing activity. Phenytoin also blocks persistent sodium current and this may be of particular importance in seizure control. Phenytoin is a class 1b antiarrhythmic [3]. 物理化学性质: CAS号:630-93-3 常用中文名:苯妥英钠 常用英文名:Phenytoin sodium 分子式:C15H11N2NaO2 分子量:274.250 密度:N/A 沸点:428.2ºC at 760 mmHg 熔点:290-299ºC 闪点:212.8ºC 储存条件:室温
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公司名:上海念兴实业有限公司 推荐
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公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
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¥165.9/100g
¥49.9/25g
¥643.9/500g
¥528.9/1ml
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公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
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¥98.0/25g
¥258.0/100g
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公司名:苏州市森菲达化工有限公司
区域:苏州市相城区
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¥需询单/200kg
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苯妥英钠价格为, 由苯妥英钠生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:苯妥英钠_价格_生产厂家【上海念兴实业有限公司】
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