常春藤皂苷元3-O-α-L-吡喃鼠李糖-(1→2)-β-D-吡喃葡萄糖-(1→4)-α-L-吡喃阿拉伯糖苷

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更新时间： 2025-12-30 08:57:08

CAS号：68027-15-6

常用名： 白头翁皂苷 D

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纯度： 96.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Pulsatilla saponin D(SB365) isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer.IC50 value:Target:SB365 effectively inhibited the growth of gastric cancer cells. Its apoptotic effect was accompanied by increased evidence of cleaved caspase-3 and poly(ADP ribose) polymerase. To elucidate the anticancer mechanism of SB365, we used an array of 42 different receptor tyrosine kinases (RTKs). Of the 42 different phospho-RTKs, SB365 strongly inhibited expression of activated c-mesenchymal-epithelial transition factor (c-Met) in gastric cancer cells [1]. SB365 strongly suppressed the growth and proliferation of 5 human pancreatic cancer cell lines (MIAPaCa-2, BXPC-3, PANC-1, AsPC-1 and HPAC). The apoptotic effect of SB365 was demonstrated by increased levels of cleaved caspase-3 and decreased Bcl-2 expression via mitochondrial membrane potential, as well as elevated numbers of terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling (TUNEL)-positive apoptotic cells [2]. SB365 strongly suppressed the growth and proliferation of colon cancer cells and induced their apoptosis. Also, SB365 showed anti-angiogenic activity by decreasing the expression of HIF-1α and VEGF. These results were confirmed by an in vivo study showing that SB365 significantly inhibited tumor growth by the induction of apoptosis and inhibition of angiogenesis with stronger anticancer activity than 5-FU [3]. 物理化学性质： CAS号：68027-15-6 常用中文名：白头翁皂苷 D 常用英文名：Pulsatilla saponin D 分子式：C47H76O17 分子量：913.096 密度：1.4±0.1 g/cm3 沸点：997.6±65.0 °C at 760 mmHg 熔点：N/A 闪点：285.4±27.8 °C 储存条件：-20°C

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公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

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网址：http://www.echemcloud.com

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2022-03-04 价格：￥2031.0 白头翁皂苷D

2019-03-05 价格：￥2388.0 白头翁皂苷D

2025-12-29 价格：￥需询单白头翁皂苷D

2024-07-15 价格：需询单常春藤皂苷元3-O-α-L-吡喃鼠李糖-(1→2)-β-D-吡喃葡萄糖-(1→4)-α-L-吡喃阿拉伯糖苷

2017-03-23 价格：￥1800.0 白头翁皂甙D

2021-02-06 价格：￥2069.0 Pulsatilla saponin D

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白头翁皂苷 D价格

常春藤皂苷元3-O-α-L-吡喃鼠李糖-(1→2)-β-D-吡喃葡萄糖-(1→4)-α-L-吡喃阿拉伯糖苷

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