地达诺辛

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发布时间： 2024-07-15 12:36:23

CAS号：69655-05-6

常用名： 地达诺辛

价格：

纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.Target: NRTIs; HIVDidanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Didanosine demonstrated linear pharmacokinetic behavior over the dose ranges of 0.4 to 16.5 mg/kg intravenously and 0.8 to 10.2 mg/kg orally. Bioavailability of didanosine when administered as a solution with an antacid was approximately 43% for doses from 0.8 to 10.2 mg/kg in patients with AIDS and advanced AIDS-related complex. Bioavailability of didanosine from the citrate-phosphate-buffered solution, the formulation currently used in phase II and expanded access studies, was comparable to the formulation used in the phase I trials [1]. ddI might be responsible for fulminant hepatitis in all three AIDS patients. This toxic effect may be added to the list of potential adverse events occurring during ddI therapy [2]. 物理化学性质： CAS号：69655-05-6 常用中文名：地达诺辛常用英文名：2',3'-Dideoxyinosine 分子式：C10H12N4O3 分子量：236.227 密度：1.8±0.1 g/cm3 沸点：531.2±60.0 °C at 760 mmHg 熔点：193-195 °C 闪点：275.0±32.9 °C 储存条件：2-8°C

供应商信息：

公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

商品数： 403768件

电话： 18916513247

地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai

地区： 上海市普陀区

联系人： 小陈

联系人电话： 0086-021-52280163

邮件：sales@echemcloud.com

网址：http://www.echemcloud.com

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其他供应商价格：

2022-02-19 价格：￥1969.9 2',3'-二脱氧肌苷

2025-09-17 价格：￥需询单地达诺辛

2021-06-28 价格：￥需询单 2',3'-双脱氧肌苷(ddI)

2022-04-22 价格：￥需询单地达诺辛

2024-05-18 价格：￥需询单地达诺辛

2017-08-08 价格：￥需询单去羟肌苷

2021-02-06 价格：￥489.0 Didanosine

2018-02-27 价格：$需询单 2',3'-Dideoxyinosine

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地达诺辛价格

地达诺辛

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