Vidofludimus

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发布时间： 2024-07-15 12:36:28

CAS号：717824-30-1

常用名： Vidofludimus

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.IC50 value:Target: DHODH inhibitorin vitro: 4SC-101 is a potent inhibitor of human DHODH, inhibits lymphocyte proliferation, and uniquely blocks phytohemagglutinin-stimulated IL-17 production by lymphocytes [2].in vivo: In vivo Vido treatment alone most effectively reduced macroscopic and histological pathology and the numbers of CD3+ T cells. In contrast, similarly reduced nuclear signal transducer and activator of transcription 3 (STAT3) binding and IL-17 levels were observed from animals treated with Vido alone and Vido + Uri. Vido improves TNBS-induced colonic inflammation by a unique dual mode of action [1]. Oral administration of 4SC-101 effectively improved both chronic DSS and acute TNBS colitis in mice. In these colitis models the overall efficacy profile of 4SC-101 was similar to that of dexamethasone [2]. 物理化学性质： CAS号：717824-30-1 常用中文名：Vidofludimus 常用英文名：Vidofludimus 分子式：C20H18FNO4 分子量：355.360 密度：1.4±0.1 g/cm3 沸点：567.5±50.0 °C at 760 mmHg 熔点：N/A 闪点：297.0±30.1 °C 储存条件：-20℃

供应商信息：

公司名：上海念兴实业有限公司推荐

认证状态： 已认证供应商

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2024-07-15 价格：需询单 Vidofludimus

2022-11-29 价格：￥需询单 Vidofludimus(4SC-101; SC12267)

2020-12-08 价格：￥需询单 Vidofludimus

2024-03-12 价格：￥5149.9 Vidofludimus

2022-11-03 价格：￥8000.0 维多氟拉迪莫

2023-03-21 价格：￥需询单 Vidofludimus;4SC-101

2023-09-14 价格：￥需询单 Vidofludimus

2022-05-12 价格：$需询单 Vidofludimus

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Vidofludimus价格

Vidofludimus

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