多沙唑嗪

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发布时间： 2024-07-15 12:36:36

CAS号：74191-85-8

常用名： 多沙唑嗪

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纯度： 98.0%

备货期： 10天

库存： 现货

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用途： Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.Target: Adrenergic ReceptorDoxazosin is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms [1]. doxazosin may have a direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. The inhibition of cholesterol synthesis by doxazosin may cause cells to compensate by upregulating the LDL receptor, thereby increasing the importation of lipoprotein cholesterol and reducing LDL cholesterol in the medium [2]. Doxazosin monotherapy was effective in eight of 12 patients (66.7%), and combined therapy with a beta-blocker was effective in 11 of 12 patients (91.7%). The mean pulse rate remained constant throughout therapy. Adverse reactions were minor and transient and occurred in only three patients. Urinary and plasma catecholamine levels tended to decrease or remained unchanged during doxazosin therapy [3].Clinical indications: Hypertension; Prostate hyperplasiaFDA Approved Date: February 22, 2005Toxicity: Symptoms of overdose include hypotension 物理化学性质： CAS号：74191-85-8 常用中文名：多沙唑嗪常用英文名：Doxazosin 分子式：C23H25N5O5 分子量：451.48 密度：1.371 g/cm3 沸点：718ºC at 760 mmHg 熔点：289-290°C 闪点：388ºC 储存条件：-20℃

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公司名：上海念兴实业有限公司推荐

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2022-03-04 价格：￥230.9 多沙唑嗪

2024-07-15 价格：需询单多沙唑嗪

2021-02-06 价格：￥3293.0 Doxazosin

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