9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺
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发布时间: 2024-07-15 12:36:52
CAS号:80012-43-7
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纯度: 98.0%
备货期: 10天
库存: 现货
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用途: Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.Target: Histamine ReceptorEpinastine shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. Epinastine inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs [1]. Epinastine is able to displace specific [3H]NC-5Z binding at low concentrations in the locust nervous tissue. Epinastine binds to the honey bees neuronal octopamine receptor with Ki of 1.1 nM. Epinastine antagonises octopamine-induced cAMP formation in the insect brain [2]. Epinastine causes an inhibition of histamine release from rat peritoneal mast cells induced by both antigen-antibody reaction and compound 48/80. Epinastine is similarly effective in inhibiting compound 48/80-induced histamine release not only from isolated rat peritoneal mast cells but also from rat mesenterial pieces. Epinastine is effective in inhibiting not only Ca2+ uptake into lung mast cells in actively sensitized guinea pigs but also Ca2+ release from the intracellular Ca store of rat peritoneal mast cells exposed to both compound 48/80 and substance P [3]. Epinastine shows a dose- and time-dependent suppressive effect on IL-8, one of the chemokines for eosinophils, released from eosinophils isolated from atopic diseases [4]. 物理化学性质: CAS号:80012-43-7 常用中文名:依匹斯汀 常用英文名:Epinastine 分子式:C16H15N3 分子量:249.31000 密度:1.32 g/cm3 沸点:428ºC at 760 mmHg 熔点:270ºC 闪点:212.7ºC 储存条件:2-8℃
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公司名:上海念兴实业有限公司 推荐
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公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
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公司名:上海阿摩尔生物科技有限公司
区域:上海市奉贤区
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9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺价格为, 由9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺_价格_生产厂家【上海念兴实业有限公司】
标题:9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺 - 生产厂家:上海念兴实业有限公司 地址:https://m.chemsrc.com/mip/chanpin/6973461.html