Nafamostat hydrochloride?
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发布时间: 2024-07-15 12:36:53
CAS号:80251-32-7
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纯度: 98.0%
备货期: 10天
库存: 现货
其他详情(用途,包装):
用途: Nafamostat hydrochloride, a synthetic serine protease inhibitor, is an anticoagulant.Target: Serine ProteaseTranilast (FUT-175) is an antiallergic drug for bronchial asthma. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. It has also been investigated for use as an antiproliferative drug on drug-eluting stents.A 20-40 mg/h dose of FUT-175 prolonged coagulation time sufficiently in the instrumental blood of the extracorporeal circuit but not in the systemic blood. Its anticoagulant activity decreased immediately after hemodialysis. Therefore, we could manage all patients without any bleeding trouble during hemodialysis with FUT-175 as an anticoagulant. Although there were side effects of FUT-175, such as nausea, vomiting, itching and eruption, they were not serious, and FUT-175 could be administered without interruption. FUT-175 seems to be useful as an anticoagulant during hemodialysis for patients susceptible to bleeding. 物理化学性质: CAS号:80251-32-7 常用中文名:Nafamostat盐酸盐 常用英文名:Nafamostat (hydrochloride) 分子式:C19H19Cl2N5O2 分子量:420.29 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃
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