米那普仑盐酸盐
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发布时间： 2024-07-15 12:37:45
CAS号：92623-85-3
常用名：
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纯度： 98.0%
备货期： 10天
库存： 现货
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用途： Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia.Target: SNRIMilnacipran (Ixel, Savella, Dalcipran, Toledomin) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.Milnacipran inhibits the reuptake of serotonin and norepinephrine in an approximately 1:3 ratio, respectively; in practical use this means a relatively balanced action upon bothneurotransmitters. Increasing both neurotransmitters concentration simultaneously works synergistically to treat both depression and fibromyalgia. Milnacipran exerts no significant actions onH1, α1, D1, D2, and mACh receptors, as well as on benzodiazepine and opioid binding sites. Milnacipran is well absorbed after oral dosing and has a bioavailability of 85%. Meals do not have an influence on the rapidity and extent of absorption. Peak plasma concentrations are reached 2 hours after oral dosing. The elimination half-life of 8 hours is not increased by liver impairment and old age, but by significant renal disease. Milnacipran is conjugated to the inactive glucuronide and excreted in the urine as unchanged drug and conjugate. Only traces of active metabolites are found. 物理化学性质： CAS号：92623-85-3 常用中文名：米那普仑 常用英文名：(-)-Milnacipran 分子式：C15H22N2O 分子量：246.348 密度：1.1±0.1 g/cm3 沸点：393.0±21.0 °C at 760 mmHg 熔点：228-228.5ºC 闪点：191.5±22.1 °C 储存条件：2-8°C，密封，干燥
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公司名：上海念兴实业有限公司 推荐
认证状态： 已认证供应商
商品数： 403768件
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地址： 2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
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2024-07-15 价格：需询单
2016-10-24 价格：￥需询单
2021-02-06 价格：￥1889.0
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米那普仑盐酸盐价格为, 由米那普仑盐酸盐生产厂家上海念兴实业有限公司提供，供应信息包括纯度，备货期/库存，供货能力等。>>电脑版：米那普仑盐酸盐_价格_生产厂家【上海念兴实业有限公司】
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