SumatriptanSuccinate

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更新时间： 2025-09-04 13:07:04

CAS号：103628-48-4

常用名： 琥珀酸舒马普坦

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Sumatriptan succinate (GR 43175) is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache.Target: 5-HT 1d receptor agonistSumatriptan succinate is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache. Its antimigraine activity is believed to derive from selective vasoconstriction of cranial blood vessels which are dilated and distended during migraine headache and/or from inhibition of neurogenically mediated inflammation in the dura mater [1].For sumatriptan succinate 50 mg versus placebo the NNTs were 6.1, 7.5, and 4.0 for pain-free at two hours and headache relief at one and two hours, respectively. NNTs for sustained pain-free and sustained headache relief during the 24 hours postdose were 9.5 and 6.0, respectively [2]. Difference in time-weighted (0-2.5 h) mean arterial pressure MAP (90% confidence interval) was 1.2 mmHg (-0.2, 2.7) between telcagepant and placebo, 4.0 mmHg (2.5, 5.5) between sumatriptan succinate and placebo, and 1.5 mmHg (0.0, 3.0) between telcagepant with sumatriptan succinate vs sumatriptan succinate alone. When coadministered with telcagepant, the AUC0-6h and C(max) of sumatriptan succinate were increased by 23% and 24%, respectively. The small MAP increases observed after coadministration could possibly be associated with the slight elevations in sumatriptan succinate levels [3].Clinical indications: Cluster headache; MigraineToxicity: Symptoms of overdose include convulsions, tremor, paralysis, inactivity, ptosis, erythema of the extremities, abnormal respiration, cyanosis, ataxia, mydriasis, salivation, and lacrimation 物理化学性质： CAS号：103628-48-4 常用中文名：琥珀酸舒马普坦常用英文名：Sumatriptan succinate 分子式：C18H27N3O6S 分子量：341.426 密度：1.2±0.1 g/cm3 沸点：497.7ºC at 760 mmHg 熔点：165-166°C 闪点：254.8ºC 储存条件：Store at +4°C

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公司名：上海化源世纪贸易有限公司推荐

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其他供应商价格：

2022-02-19 价格：￥199.9 琥珀酸舒马坦

2026-03-10 价格：￥需询单琥珀酸舒马曲普坦

2021-05-10 价格：￥需询单琥珀酸舒马曲坦

2020-12-08 价格：￥456.0 sumatriptan succinate

2022-05-12 价格：$需询单 Sumatriptan succinate

2024-04-29 价格：￥需询单琥珀酸舒马普坦

2024-01-09 价格：$需询单 Sumatriptan succinate

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SumatriptanSuccinate

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