利塞膦酸

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更新时间： 2025-08-21 16:49:18

CAS号：105462-24-6

常用名： 利塞膦酸

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纯度： 99.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Risedronic acid (Risedronate ) is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.Target: OthersRisedronate, which was promoted in Croatia a few months ago, is the latest (III) generation of bisphosphonates, the most efficient anti-resorption drugs that inhibit osteoclast-mediated bone resorption and change the bone metabolism. Risedronate is hence the first line of bisphosphonates for the reduction of vertebral and non-vertebral fracture risks in postmenopausal women with osteoporosis or those with a high risk of osteoporosis. It also efficiently prevents bone loss or improves bone density in men and women on a long-term corticosteroid therapy .The administration of 20 and 25 mg/kg risedronate for 4 days led to decreases of parasitemia of 68.9% and 83.6%, respectively. On the seventh day of treatment the inhibitions were 63% and 88.9% with 20 and 25 mg/kg, respectively. After recovering the parasitemia, a dose-response curve was obtained for estimating the ID50 (dose causing 50% inhibition), equivalent to 17 ± 1.8 mg/kg after 7 days of treatment. Four days after the interruption of treatment (11 days postinfection), the parasitemias of the groups treated with 10, 15, 20, and 25 mg/kg/day were 15.3%, 15.9%, 15.2%, and 5.7%, respectively. Conversely, the group that received PBS presented parasitemia of 25.6%. Among the groups treated with risedronate, only the animals that received 25 mg/kg had a significant inhibition of 77.8% (see Table S1 in the supplemental material), demonstrating that even after treatment discontinuation, the parasitemia of the animals remained low in relation to that of the controls . 物理化学性质： CAS号：105462-24-6 常用中文名：利塞膦酸常用英文名：Risedronic acid 分子式：C7H11NO7P2 分子量：283.112 密度：1.9±0.1 g/cm3 沸点：692.3±65.0 °C at 760 mmHg 熔点：N/A 闪点：372.5±34.3 °C 储存条件：2~8°C

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其他供应商价格：

2019-03-05 价格：￥408.0 利塞膦酸

2022-11-29 价格：￥需询单 Risedronic acid (Actonel)

2021-02-06 价格：￥789.0 Risedronate

2022-02-19 价格：￥141.0 利塞膦酸

2025-01-08 价格：￥需询单利塞膦酸

2024-09-13 价格：￥需询单利塞膦酸

2017-07-11 价格：￥需询单利塞膦酸

2017-12-18 价格：￥需询单利塞膦酸

2023-05-17 价格：￥需询单利塞膦酸

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利塞膦酸

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