那格列奈

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更新时间： 2025-09-15 10:06:19

CAS号：105816-04-4

常用名： 那格列奈

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).Target: OthersNateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal. Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. The average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those na?ve to oral antidiabetic agents. Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose. In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones. Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. One minor metabolite, the isoprene, has the same potency as its parent compound [1-3]. 物理化学性质： CAS号：105816-04-4 常用中文名：那格列奈常用英文名：Nateglinide 分子式：C19H27NO3 分子量：317.423 密度：1.1±0.1 g/cm3 沸点：527.6±39.0 °C at 760 mmHg 熔点：137-141ºC 闪点：272.9±27.1 °C 储存条件：Room temp

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其他供应商价格：

2022-02-19 价格：￥48.9 那格列奈

2019-03-05 价格：￥168.0 那格列奈

2024-09-13 价格：￥需询单那格列奈

2017-07-07 价格：￥需询单那格列奈

2020-12-08 价格：￥800.0 那格列奈

2018-10-25 价格：￥需询单那格列奈 105816-04-4

2018-09-13 价格：￥需询单那格列奈

2018-03-30 价格：￥需询单那格列奈

2018-02-14 价格：￥需询单那格列奈

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