Marbofloxacin hydrochloride?
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更新时间： 2025-08-22 15:14:06
CAS号：115551-26-3
常用名：
价格：
纯度： 98.0%
备货期： 10天
库存： 现货
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用途： Marbofloxacin hydrochloride is a potent antibiotic of which depends upon its inhibition of DNA-gyrase.Target: DNA-gyraseMarbofloxacin hydrochloride is a third-generation fluoroquinolone for veterinary use, the antimicrobial of which depends upon its inhibition of DNA-gyrase and topoisomerase IV. With a broad spectrum bactericidal activity and good efficacy, marbofloxacin hydrochloride is indicated for dermatological, respiratory and urinary tract infections due to both Gram-positive and Gram-negative bacteria and Mycoplasma [1].Administration of Marbofloxacin hydrochloride at 6 mg/kg once daily for 7 days in a Staphylococcus aureus infection in tissue cages in ponies is not effective for the elimination of S. aureus infections from secluded sites [2]. The pharmacokinetic properties of marbofloxacin hydrochloride were investigated in 6 horses after i.v., subcutaneous and oral administration of a single dose of 2 mg/kg bwt and the minimal inhibitory concentrations (MIC) assessed for bacteria isolated from equine infectious pathologies. The clearance of marbofloxacin hydrochloride was mean +/- s.d. 0.25 +/- 0.05 l/kg/h and the terminal half-life 756 +/- 1.99 h. The marbofloxacin hydrochloride absolute bioavailabilities after subcutaneous and oral administration were 98 +/- 11% and 62 +/- 8%, respectively. Considering the breakpoint values of efficacy indices for fluoroquinolones, a marbofloxacin hydrochloride dosage regimen of 2 mg/kg bwt/24 h by i.v., subcutaneous or oral routes was more appropriate for enterobacteriaceae than for S. aureus [3]. Toxicity: cramps; vomiting; anorexia; soft stools; diarrhoea 物理化学性质： CAS号：115551-26-3 常用中文名：盐酸马博沙星 常用英文名：Marbofloxacin (hydrochloride) 分子式：C17H20ClFN4O4 分子量：398.81700 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃
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Marbofloxacin hydrochloride?价格为, 由Marbofloxacin hydrochloride?生产厂家上海化源生化科技有限公司提供，供应信息包括纯度，备货期/库存，供货能力等。>>电脑版：Marbofloxacin hydrochloride?_价格_生产厂家【上海化源生化科技有限公司】
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