盐酸万乃洛韦
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更新时间: 2025-08-20 17:27:54
CAS号:124832-27-5
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纯度: 98.0%
备货期: 10天
库存: 现货
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用途: Valacyclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Target: HSVValacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. VACV uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64 +/- 0.06 mM and 23.34 +/- 0.36 nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro . For treatment of a first episode of genital herpes, a large comparative trial has shown that valacyclovir (1 g twice a day) is as effective as acyclovir (200 mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200 mg five times a day) with a treatment period of 5 days. A daily dose of 1 g of valacyclovir is as effective as 2 g daily. Valacyclovir can be administered once a day. The concentrations of acyclovir in serum and CSF were measured at steady state after 6 days of oral treatment with 1,000 mg of valacyclovir three times a day. EC50 values of PE and AC in 3T3 cells were 0.02 and 0.01 ug/ml, while values in BHK cells were 0.2 and 0.03 ug/ml. Treatment of infected immunosuppressed mice and FA and VA (b.i.d., 5.5 days) reduced the proportion with erythema from 100% to 24% and 38%, and eliminated ear paralysis, ear lesions (vesicles, etc) and death. Virus was absent from ear and brainstem by day 6, but reappeared after discontinuation in mice treated with VA. 物理化学性质: CAS号:124832-27-5 常用中文名:盐酸伐昔洛韦 常用英文名:Valacyclovir hydrochloride 分子式:C13H21ClN6O4 分子量:360.797 密度:1.55g/cm3 沸点:588.4ºC at 760 mmHg 熔点:170-172ºC 闪点:309.7ºC 储存条件:Refrigerator
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盐酸万乃洛韦价格为, 由盐酸万乃洛韦生产厂家上海化源世纪贸易有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:盐酸万乃洛韦_价格_生产厂家【上海化源世纪贸易有限公司】
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