毛蕊异黄酮

产品详情：

发布时间： 2024-07-15 12:33:29

CAS号：20575-57-9

常用名： 毛蕊异黄酮

价格：

纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Calycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.IC50 value:Target: in vitro: calycosin had obvious anti-proliferation effects on SKOV3 cells in a dose- and time-dependent manner. calycosin up-regulated the Bax/Bcl-2 ratio and cleaved caspase-3, cleaved caspase-9 expression in a dose-dependent manner. In summary, calycosin might exert anti-growth and induce-apoptosis activity against ovarian cancer SKOV3 cells through activating caspases and Bcl-2 family proteins, therefore presenting as a promising therapeutic agent for the treatment of ovarian cancer [1]. Both calycosin and genistein inhibited proliferation and induced apoptosis in MCF-7 breast cancer cells, especially after treatment with calycosin. Treatment of MCF-7 cells with calycosin or genistein resulted in decreased phosphorylation of Akt, and decreased expression of its downstream target, HOTAIR [2]. incubation of calycosin resulted in enhanced expression ERβ in MCF-7 and T-47D cells, rather than MDA-231 and MDA-435 cells. Moreover, with the upregulation of ERβ, successive changes in downstream signaling pathways were found, including inactivation of insulin-like growth factor 1 receptor (IGF-1R), then stimulation of p38 MAPK and suppression of the serine/threonine kinase (Akt), and finally poly(ADP-ribose) polymerase 1 (PARP-1) cleavage [3].in vivo: calycosin stimulated a dramatic increase in uterine weight and downregulated the level of ERα protein in OVX mice [4]. 物理化学性质： CAS号：20575-57-9 常用中文名：毛蕊异黄酮常用英文名：Calycosin 分子式：C16H12O5 分子量：284.263 密度：1.4±0.1 g/cm3 沸点：536.8±50.0 °C at 760 mmHg 熔点：N/A 闪点：205.7±23.6 °C 储存条件：2-8°C

供应商信息：

公司名：上海化源世纪贸易有限公司推荐

认证状态： 已认证供应商

商品数： 396724件

电话： 13311869306

地址： 上海市普陀区金沙江路1759号圣诺亚大厦A座1116室

地区： 上海市普陀区

联系人： 徐经理

联系人电话： 13311869306

邮件：xuqm@chemsrc.com

网址：http://www.chemsrc.com

公司介绍：
化源网 www.echemsrc.com ，国内知名化学品商城，品牌全，价格优，操作更智能，详情欢迎咨询！

其他供应商价格：

2024-09-29 价格：￥需询单毛蕊异黄酮

2019-03-05 价格：￥788.0 毛蕊异黄酮

2022-11-29 价格：￥需询单 Calycosin

2021-02-06 价格：￥2489.0 Calycosin

2022-02-19 价格：￥931.9 毛蕊异黄酮

2021-12-23 价格：￥1682.0 [Perfemiker]毛蕊异黄酮,≥98%(HPLC)

2022-12-09 价格：￥需询单毛蕊异黄酮

2016-03-11 价格：￥800.0 毛蕊异黄酮

2023-11-02 价格：￥300.0 毛蕊异黄酮

查看所有价格请点击：

毛蕊异黄酮价格

毛蕊异黄酮

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：