Edoxaban

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更新时间： 2025-08-22 17:54:16

CAS号：480449-71-6

常用名： 伊多塞班对甲苯磺酸盐

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke preventionIC50 Value:Target: factor XaEdoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammatory drugs for concurrent illnesses[1].in vitro: Edoxaban PK was not affected by concomitant low-dose ASA or naproxen, but high-dose ASA increased systemic exposure of edoxaban by approximately 30%. The effects of edoxaban on prothrombin time, activated partial thromboplastin time, international normalized ratio, anti-FXa, and intrinsic FXa activity were not influenced by administration with ASA or naproxen. Inhibition of platelet aggregation by high-dose ASA, low-dose ASA, or naproxen was not affected by edoxaban[1].in vivo: Forty-eight subjects, aged 18 to 45 years, received either edoxaban 60 mg once daily × 7 days (n = 24) or digoxin 0.25 mg twice daily × 2 days and once daily × 5 days (n = 24) and then concomitantly for 7 days. Serial blood and urine samples were collected for digoxin and edoxaban concentrations on days 7 and 14. Serial coagulation assays were measured for edoxaban on days 7 and 14. Edoxaban PK parameters demonstrated mild increases in area under the curve and peak concentrations of 9.5% and 15.6%, respectively[2],Clinical trial: Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans was reported[3]. 物理化学性质： CAS号：480449-71-6 常用中文名：伊多塞班对甲苯磺酸盐常用英文名：edoxaban tosylate 分子式：C31H38ClN7O7S2 分子量：720.259 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃

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化源网，2015 年正式成立，是专注服务全球精细化学与生物医药研发领域的专业社群电商平台。
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其他供应商价格：

2025-02-05 价格：￥499.9 依度沙班对甲苯磺酸盐

2022-01-07 价格：￥需询单 Edoxaban Tosylate Monohydrate

2021-04-03 价格：￥需询单 Edoxaban (tosylate)

2021-10-18 价格：￥1000.0 依度沙班对甲苯磺酸盐 (Edoxaban (tosylate))

2021-12-21 价格：￥6000.0 依度沙班对甲苯磺酸盐

2017-07-03 价格：￥需询单甲苯磺酸依度沙班

2024-01-09 价格：$需询单 C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6

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伊多塞班对甲苯磺酸盐价格

Edoxaban

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