2-(4-(叔丁基)苯基)-1H-苯并[d]咪唑

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发布时间： 2024-07-15 12:35:27

CAS号：49671-76-3

常用名： 2-(4-叔丁基苯基)苯并咪唑

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纯度： 98.0%

备货期： 10天

库存： 现货

其他详情（用途，包装）：
用途： ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).IC50 value:Target: PGC-1αin vitro: ZLN005 increases expression of the PGC-1α gene in L6 myotubes. ZLN005 increased PGC-1α mRNA levels in a dose-dependent manner; 20 μmol/L ZLN005 caused a threefold increase over the control after 24 h. At 10 μmol/L, the PGC-1α mRNA levels were increased to almost the same extent at 16 to 48 h [1]. ZLN005 did not increase the expression of the PGC-1α gene in rat primary hepatocytes. AMP-activated protein kinase is involved in the mechanism inducing PGC-1α in L6 myotubes [1]in vivo: An insulin tolerance test revealed that treatment with ZLN005 significantly decreased insulin resistance in db/db mice, as evidenced by the approximately 18% decrease in the AUC. A PTT also was performed in db/db mice, and ZLN005 improved pyruvate tolerance, as evidenced by the 16% decrease in the AUC. In db/db mice, plasma NEFA and triglyceride levels were decreased by 20% and 37%, respectively, and cholesterol was decreased by 10% with ZLN005 treatment. Plasma insulin and β-hydroxybutyrate content, liver/bodyweight index and adipose composition, and muscle and liver triglyceride levels, however, were not ameliorated by treatment with ZLN005 or metformin [1]. 物理化学性质： CAS号：49671-76-3 常用中文名：2-(4-叔丁基苯基)苯并咪唑常用英文名：ZLN005 分子式：C17H18N2 分子量：250.338 密度：1.1±0.1 g/cm3 沸点：415.3±38.0 °C at 760 mmHg 熔点：257-258℃ 闪点：205.4±13.2 °C 储存条件：2~8°C，密封

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公司名：上海化源世纪贸易有限公司推荐

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商品数： 396743件

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联系人： 徐乾明

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邮件：xuqm@chemsrc.com

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其他供应商价格：

2022-11-29 价格：￥需询单 ZLN005

2020-12-08 价格：￥6500.0 ZLN005

2022-02-19 价格：￥277.9 ZLN005

2021-12-23 价格：￥2184.0 [Perfemiker]2-(4-叔丁基苯基)苯并咪唑,98%

2018-04-16 价格：￥需询单 ZLN005

2017-12-26 价格：￥需询单 2-(4-tert-butylphenyl)-1H-benzimidazole

2023-09-06 价格：￥需询单 ZLN005

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2-(4-叔丁基苯基)苯并咪唑价格

2-(4-(叔丁基)苯基)-1H-苯并[d]咪唑

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