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文拉法辛

产品详情:

更新时间: 2025-09-15 11:16:37

CAS号:93413-69-5

常用名: D,L-文拉法辛

价格:

纯度: 98.0%

备货期: 10天

库存: 现货

其他详情(用途,包装):
用途: Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.Target: SNRIVenlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. In 2007, venlafaxine was the sixth most commonly prescribed antidepressant on the U.S. retail market, with 17.2 million prescriptions.Venlafaxine is a bicyclic antidepressant, and usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It works by blocking the transporter "reuptake" proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotransmitters affected are serotonin and norepinephrine. Additionally, in high doses it weakly inhibits the reuptake of dopamine, with recent evidence showing that the norepinephrine transporter also transports some dopamine as well, since dopamine is inactivated by norepinephrine reuptake in the frontal cortex. The frontal cortex largely lacks dopamine transporters; therefore, venlafaxine can increase dopamine neurotransmission in this part of the brain. Venlafaxine interacts with opioid receptors (mu-, kappa1- kappa3- and delta-opioid receptor subtypes) as well as the alpha2-adrenergic receptor, and was shown to increase pain threshold in mice. When mice were tested with a hotplate analgesia meter (to measure pain), both venlafaxine and mirtazapine induced a dose-dependent, naloxone-reversible antinociceptive effect following intraperitoneal injection. These findings suggest venlafaxine's seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. 物理化学性质: CAS号:93413-69-5 常用中文名:D,L-文拉法辛 常用英文名:Venlafaxine 分子式:C17H27NO2 分子量:277.402 密度:1.1±0.1 g/cm3 沸点:397.6±27.0 °C at 760 mmHg 熔点:72-74°C 闪点:194.2±23.7 °C 储存条件:Refrigerator, Under Inert Atmosphere

供应商信息:

公司名:上海化源世纪贸易有限公司 推荐

认证状态: 已认证供应商

商品数: 396716件

电话: 53555033

地址: 上海市普陀区金沙江路1759号圣诺亚大厦B座

地区: 上海市普陀区

联系人: 徐经理

联系人电话: 13311869306

邮件:xuqm@chemsrc.com

网址:http://www.chemsrc.com

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公司介绍:
化源网,2015 年正式成立,是专注服务全球精细化学与生物医药研发领域的专业社群电商平台。
平台严选优质品牌商家直供,以正品低价为核心优势,搭配简洁易操作的商城界面,为研发人员提供一站式采购方案,全程保障高效便捷的服务体验。

推荐生产厂家/供应商:

公司名:上海阿拉丁生化科技股份有限公司

区域:上海市浦东新区

价格:
¥3853.9/1g ¥1411.9/250mg ¥411.9/50mg ¥514.9/1ml

联系人:阿拉丁

产品详情: D,L-文拉法辛


公司名:苏州市森菲达化工有限公司

区域:苏州市相城区

价格:
¥需询单/200kg

联系人:程经理

产品详情: 文拉法辛


公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情: 文拉法辛


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其他供应商价格:

2022-03-04 价格:¥3853.9 D,L-文拉法辛

2026-03-10 价格:¥需询单 文拉法辛

2017-07-07 价格:¥需询单 盐酸文拉法辛碱

2024-01-09 价格:$需询单 Venlafaxine

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文拉法辛价格为, 由文拉法辛生产厂家上海化源世纪贸易有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:文拉法辛_价格_生产厂家【上海化源世纪贸易有限公司】

标题:文拉法辛 - 生产厂家:上海化源世纪贸易有限公司 地址:https://m.chemsrc.com/mip/chanpin/7416595.html