Wnt-p53 inhibitor compound 2
产品详情:
发布时间: 2024-07-17 16:20:58
CAS号:1448427-02-8
常用名:
价格:
¥需询单/100mg
¥需询单/250mg
¥需询单/1g
纯度: 98.0%
备货期: 10天
库存: 现货
其他详情(用途,包装):
用途: Wnt-p53 inhibitor compound 2 is a novel inhibitor targets both Wnt signaling and ATM/p53, potently inhibits Wnt transcription (IC50=11 nM) and p53 transcription (EC50=1.9 nM); decreases HCT-116 CRC cell viability (IC50=10 nM) and proliferation (IC50=8 nM), decreases DLD-1, SW480 and 10.1 cancer cell viability (IC50=12, 27 and 41 nM) and proliferation (IC50=18,15 and 13 nM); compound 2 potently activates apoptosis of HCT-116, DLD-1 and SW480 cells (EC50=13, 15 and 18 nM) in a p53-dependent manner; inhibits cell migration and invasion in HCT-116 at 20-200 nM, also modulates mitotic stress signaling, leading to both inhibition of Wnt responsiveness and stabilization and activation of p53 to cause cell cycle arrest; induces cell death and inhibits tumor growth in mouse xenografts (20 mg/kg/day, i.p.), without acute cytotoxicity nor toxicity. 物理化学性质: CAS号:1448427-02-8 常用中文名:Wnt-p53 inhibitor compound 2 常用英文名:Wnt-p53 inhibitor compound 2 分子式:C19H21N3O3S 分子量:371.455 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A
供应商信息:
公司名:上海念兴实业有限公司 推荐
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Wnt-p53 inhibitor compound 2价格为¥需询单/100mg, 由Wnt-p53 inhibitor compound 2生产厂家上海念兴实业有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:Wnt-p53 inhibitor compound 2_价格_生产厂家【上海念兴实业有限公司】
标题:Wnt-p53 inhibitor compound 2 - 生产厂家:上海念兴实业有限公司 地址:https://m.chemsrc.com/mip/chanpin/7463393.html