盐酸胺碘酮
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更新时间: 2026-06-12 21:17:57
CAS号:19774-82-4
常用名:
价格:
¥需询单/200kg
纯度: 98.0%
备货期: 需询单
库存: 现货
其他详情(用途,包装):
用途: Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. IC50 Value: 1.5 uM ( inhibit TBARS, LOOH and FPL formation)[1]in vitro: It was found that 10 uM amiodarone induces accumulation of ethidium bromide (5 ug/ml) in Saccharomyces cerevisiae cells. At the same time, in yeast cells with inactivated MDR genes, accumulation of ethidium bromide was 6-fold higher even without amiodarone. Addition of non-lethal concentrations of amiodarone to MDR-deficient cells caused an increase of intracellular ethidium bromide to the level, which was even lower than the level in amiodarone-treated wild-type cells [2]. Cells treated with amiodarone were seen to have detached from the dish, with cell rounding, cytoplasmic blebbing and irregularity in shape. An increase in the sub-G1 phase fraction, from 15.43 to 21.34% and 79.83% and a reduction in the G1 phase fraction, from 48.83 to 41.63% and 11.52%, were observed in cells treated with amiodarone at concentrations of 0.1 and 1 mM, respectively [3].in vivo: Chronic treatment with oral amiodarone for 4 weeks reduced i.p. when myocytes were dialyzed with patch-pipettes containing either 10 mM Na+ or 80 mM Na+. In myocytes from untreated rabbits, acute exposure to amiodarone in vitro reduced i.p. when patch pipettes contained 10 mM Na+ but had no effect on i.p. at 80 mM Na+. Amiodarone had no effect on the voltage dependence of the pump or the affinity of the pump for extracellular K+ either after chronic treatment or during acute exposure [4].Clinical trial: Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial Fibrillation . Phase not specified 物理化学性质: CAS号:19774-82-4 常用中文名:盐酸胺碘酮 常用英文名:Amiodarone HCl 分子式:C25H30ClI2NO3 分子量:681.773 密度:1.58 g/cm3 沸点:635.1ºC at 760 mmHg 熔点:154-158°C 闪点:337.9ºC 储存条件:2-8°C
供应商信息:
公司名:苏州市森菲达化工有限公司 推荐
认证状态: 已认证供应商
商品数: 20000件
电话: 0512-18796480002
地址: 苏州市高新区浒墅关经济技术开发区
地区: 苏州市相城区
联系人: 程经理
联系人电话: 18796480002
邮件:13771713870@163.com
主要市场:国内,海外
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公司介绍:
苏州市森菲达化工有限公司,位于苏州市高新区浒墅关经济技术开发区。是由一群高分子精细化工专业人员组建而成的,专为客户提供配套化学原料。为解决客户的实质问题,我们专注于引入新产品,带入新思路,尤在 3D打印、UV光固化方面有先进的功能性原材料和强大的技术后盾。 自有的合成研发团队与应用实验室,并投资入股在湖南岳阳的化工厂,长期定制**。
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我们的经营理念:永续经营,创造利润,分享顾客。
服务宗旨:坚持品质**,信誉为本,用户至上之原则,以“品质、服务、诚信、服务”为理念,和广大新老客户共创。
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公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
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公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
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公司名:盼得(上海)国际贸易有限公司
区域:上海市徐汇区
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公司名:江西瑞威尔生物科技有限公司
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公司名:上海化源世纪贸易有限公司
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盐酸胺碘酮价格为¥需询单/200kg, 由盐酸胺碘酮生产厂家苏州市森菲达化工有限公司提供,供应信息包括纯度,备货期/库存,供货能力等。>>电脑版:盐酸胺碘酮_价格_生产厂家【苏州市森菲达化工有限公司】
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