地拉考昔

产品详情：

更新时间： 2026-03-11 15:13:45

CAS号：169590-41-4

常用名： 地拉考昔

价格：
￥需询单/200kg

纯度： 98.0%

备货期： 需询单

库存： 现货

其他详情（用途，包装）：
用途： Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). IC50 Value: 70 to 150 uM(inhibition of 3 osteosarcoma cell lines) [1]Target: COXin vitro: Concentration of deracoxib required for 50% inhibition of cell viability (IC50) was reached in all 3 osteosarcoma cell lines and ranged from 70 to 150 microM, whereas the IC50 for piroxicam was only reached in the POS cell line at 500 microM. Neither deracoxib nor piroxicam induced sufficient toxicity in fibroblasts to reach an IC50. Exposure of osteosarcoma cells to cytotoxic concentrations of deracoxib and piroxicam did not result in DNA fragmentation [1]. Concomitant treatment of cells with piroxicam and deracoxib resulted in significant induction of apoptosis at lower concentrations and accumulation of cells in the G /G phase. Significant cytotoxic effects exhibited by the combination of piroxicam and deracoxib against canine mammary carcinoma cells in vitro suggest an attractive approach for the treatment of canine mammary carcinoma [2].in vivo: Perioperative administration of deracoxib to dogs at 1-2 mg/kg/day for 3 days significantly improves analgesia in the postoperative surgical period after soft tissue surgery [3]. Dogs were treated PO with deracoxib at a dosage of 3 mg/kg/d (1.36 mg/lb/d) as a single-agent treatment for TCC. Tumor response was assessed via radiography, abdominal ultrasonography, and ultrasonographic mapping of urinary bladder masses. Toxic effects of deracoxib administration in dogs were assessed through clinical observations and hematologic and biochemical analyses. 24 dogs for which tumor response was assessed, 4 (17%) had partial remission, 17 (71%) had stable disease, and 3 (13%) had progressive disease; initial response could not be assessed in 2 of 26 dogs. The median survival time was 323 days. Median time to progressive disease was 133 days. Renal, hepatic, and gastrointestinal abnormalities attributed to deracoxib administration were noted in 4% (1/26), 4% (1/26), and 19% (5/26) of dogs, respectively [4]. 物理化学性质： CAS号：169590-41-4 常用中文名：地拉考昔常用英文名：deracoxib 分子式：C17H14F3N3O3S 分子量：397.372 密度：1.5±0.1 g/cm3 沸点：575.5±60.0 °C at 760 mmHg 熔点：N/A 闪点：301.9±32.9 °C 储存条件：-20℃

供应商信息：

公司名：苏州市森菲达化工有限公司推荐

认证状态： 已认证供应商

商品数： 20000件

电话： 0512-18796480002

地址： 苏州市高新区浒墅关经济技术开发区

地区： 苏州市相城区

联系人： 程经理

联系人电话： 18796480002

邮件：13771713870@163.com

网址：http://www.senfeida.com

主要市场：国内，海外

年贸易额：

外贸占销售比例：

主要合作伙伴：

公司介绍：
苏州市森菲达化工有限公司，位于苏州市高新区浒墅关经济技术开发区。是由一群高分子精细化工专业人员组建而成的，专为客户提供配套化学原料。为解决客户的实质问题，我们专注于引入新产品,带入新思路，尤在 3D打印、UV光固化方面有先进的功能性原材料和强大的技术后盾。自有的合成研发团队与应用实验室，并投资入股在湖南岳阳的化工厂,长期定制**。

湖南岳阳基地**环氧活性稀释剂（缩水甘油醚），UV单体稀释剂、精细化工产品。

我们的经营理念：永续经营，创造利润，分享顾客。

服务宗旨：坚持品质**，信誉为本，用户至上之原则，以“品质、服务、诚信、服务”为理念，和广大新老客户共创。

其他供应商价格：

2024-03-12 价格：￥41.9 地拉考昔

2019-03-05 价格：￥1166.0 地拉考昔

2024-07-15 价格：需询单地拉考昔

2021-02-06 价格：￥9589.0 Deracoxib

查看所有价格请点击：

地拉考昔价格

地拉考昔

产品详情：

供应商信息：

推荐生产厂家/供应商：

其他供应商价格：

相关产品价格：