(R)-(-)-O-Desmethyl Venlafaxine D6

• 常用名: (R)-(-)-O-Desmethyl Venlafaxine D6
• 英文名: (R)-(-)-O-Desmethyl Venlafaxine D6
• CAS号: 1062609-96-4
• 分子量: 269.412
• 密度: 1.1±0.1 g/cm3
• 沸点: 403.8±25.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉D₆NO₂
• 熔点: N/A
• 闪点: 193.2±21.8 °C

(R)-(-)-O-Desmethyl Venlafaxine D6用途

(R)-(-)-O-Desmethyl Venlafaxine D6 是 (R)-(-)-O-Desmethyl Venlafaxine 的氘代物。O-Desmethyl Venlafaxine 是 Venlafaxine 的活性代谢产物。Venlafaxine (HY-B0196) 是 5-羟色胺-去甲肾上腺素再摄取抑制剂 (SNRI) 类的抗抑郁剂。

(R)-(-)-O-Desmethyl Venlafaxine D6名称

• 英文名: 4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol

(R)-(-)-O-Desmethyl Venlafaxine D6生物活性

• 描述: (R)-(-)-O-Desmethyl Venlafaxine D6 是 (R)-(-)-O-Desmethyl Venlafaxine 的氘代物。O-Desmethyl Venlafaxine 是 Venlafaxine 的活性代谢产物。Venlafaxine (HY-B0196) 是 5-羟色胺-去甲肾上腺素再摄取抑制剂 (SNRI) 类的抗抑郁剂。
• 相关类别:
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.

  [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

(R)-(-)-O-Desmethyl Venlafaxine D6物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 403.8±25.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉D₆NO₂
• 分子量: 269.412
• 闪点: 193.2±21.8 °C
• 精确质量: 269.226196
• LogP: 2.26
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.573

(R)-(-)-O-Desmethyl Venlafaxine D6英文别名

• 4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
• Phenol, 4-[(1R)-2-(dimethyl-d3-amino)-1-(1-hydroxycyclohexyl)ethyl]-