Benzeneethanol, a-[4-[2-(diethylamino)ethoxy]phenyl]-4-methoxy-a-phenyl

• 常用名: Benzeneethanol, a-[4-[2-(diethylamino)ethoxy]phenyl]-4-methoxy-a-phenyl
• 英文名: Benzeneethanol, a-[4-[2-(diethylamino)ethoxy]phenyl]-4-methoxy-a-phenyl
• CAS号: 67-98-1
• 分子量: 419.55600
• 密度: 1.097g/cm3
• 沸点: 542.3ºC at 760 mmHg
• 分子式: C₂₇H₃₃NO₃
• 熔点: N/A
• 闪点: 281.8ºC

用途

Ethamoxytriphetol (MER-25) 是一种非甾体抗雌激素。

名称

• 英文名: 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyphenyl)-1-phenylethanol

生物活性

• 描述: Ethamoxytriphetol (MER-25) 是一种非甾体抗雌激素。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. CLITHEROE HJ, et al. effect of estradiol and ethamoxytrlphetol (MER-25) on the Mmouse uterus. Endocrinology. 1965 Jan;76:127-30.

物理化学性质

• 密度: 1.097g/cm3
• 沸点: 542.3ºC at 760 mmHg
• 分子式: C₂₇H₃₃NO₃
• 分子量: 419.55600
• 闪点: 281.8ºC
• 精确质量: 419.24600
• PSA: 41.93000
• LogP: 4.89440
• InChIKey: KDYQVUUCWUPJGE-UHFFFAOYSA-N
• SMILES: CCN(CC)CCOc1ccc(C(O)(Cc2ccc(OC)cc2)c2ccccc2)cc1
• 折射率: 1.573

毒性和生态

靶点实验

查看更多实验

实验名称：Ability to antagonize uterine weight gain in immature mice, at a dose of 150 ug; Acti... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL736971

实验名称：Relative binding affinity evaluated from the ability to displace [3H]estradiol from e... 来源：ChEMBL 靶标：Estrogen receptor beta External Id：CHEMBL674367

实验名称：Percent relative binding affinity (RBA) for estrogen receptor compared to estradiol 来源：ChEMBL 靶标：Estrogen receptor beta External Id：CHEMBL682117

实验名称：Percentage reduction in estradiol-stimulated uterotrophic effect of immature mice at ... 来源：ChEMBL 靶标：Estrogen receptor beta External Id：CHEMBL740796

实验名称：Ability to antagonize uterine weight gain in immature mice, at a dose of 30 ug; Activ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL736974

实验名称：Antagonism of estradiol induced uterine weight gain in immature mice at 750 ug; Activ... 来源：ChEMBL 靶标：Estrogen receptor beta External Id：CHEMBL737135

实验名称：Estrogenic property of the compound; nonestrogenic 来源：ChEMBL 靶标：N/A External Id：CHEMBL638407

实验名称：Carcinogenesis bioassays from the Carcinogenic Potency Database (CPDB) 来源：25294 靶标：N/A External Id：cpdb

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

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英文别名

• (p-2-Diethylaminoethoxyphenyl)-1-phenyl-2-p-anisylethanol
• 1-[p-(2-diethylaminoethoxy)-phenyl]-2-(p-methoxyphenyl)-1-phenylethanol
• Ethamoxytriphetol
• 1-<4-(2-Diethylamino-ethoxy)-phenyl>-2-(4-methoxy-phenyl)-1-phenyl-ethanol
• Ethamoxytriphenol
• 1-<4-(2-Diethylamino-ethoxy)-phenyl>-1-phenyl-2-(4-methoxy-phenyl)-ethanol
• Ethanoxytriphetol
• 1-[4-(2-Diethylaminoethoxy)phenyl]-1-phenyl-2-(p-anisyl)ethanol
• MER 25