hispaglabridin A

• 常用名: hispaglabridin A
• 英文名: hispaglabridin A
• CAS号: 68978-03-0
• 分子量: 392.48700
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₈O₄
• 熔点: N/A
• 闪点: N/A

hispaglabridin A用途

Hispagladridin A是一种有效抑制脂质过氧化的抗氧化剂[1]。

hispaglabridin A名称

• 英文名: hispaglabridin A

hispaglabridin A生物活性

• 描述: Hispagladridin A是一种有效抑制脂质过氧化的抗氧化剂[1]。
• 相关类别:
  研究领域 >> 其他
• 体外研究: Hispagladridin A(Hispaglabridin A)抑制 纳赫依赖的大鼠肝脏线粒体脂质过氧化,国际50为 4.9μ抑制 L-抗坏血酸(HY-B0166)诱导的过氧化,国际50为 1.7μM[1]
• 参考文献:

  [1]. Haraguchi H, et al. Protection of mitochondrial functions against oxidative stresses by isoflavans from Glycyrrhiza glabra. J Pharm Pharmacol. 2000 Feb;52(2):219-23.

hispaglabridin A物理化学性质

• 分子式: C₂₅H₂₈O₄
• 分子量: 392.48700
• 精确质量: 392.19900
• PSA: 58.92000
• LogP: 5.50940
• InChIKey: HZHXMXSXYQCAIG-KRWDZBQOSA-N
• SMILES: CC(C)=CCc1c(O)ccc(C2COc3c(ccc4c3C=CC(C)(C)O4)C2)c1O

hispaglabridin A靶点实验

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实验名称：Antifungal activity against Candida albicans ATCC 10231 at 100 mcg/ml by agar-dilutio... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL1025040

实验名称：Antibacterial activity against Mycobacterium smegmatis ATCC 607 by agar-dilution stre... 来源：ChEMBL 靶标：Mycolicibacterium smegmatis External Id：CHEMBL1025038

实验名称：Antiproliferative activity against human SW480 cells at 10 uM after 24 hrs by MTS ass... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4053426

实验名称：Antibacterial activity against Salmonella gallinarum ATCC 9184 at 100 mcg/ml by agar-... 来源：ChEMBL 靶标：Salmonella enterica subsp. enterica serovar Gallinarum External Id：CHEMBL1025035

实验名称：Antibacterial activity against Klebsiella pneumoniae ATCC 10031 at 100 mcg/ml by agar... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL1025036

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Inhibition of recombinant human PTP1B using pNPP as substrate after 30 mins 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4053416

实验名称：Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM after 6 h... 来源：ChEMBL 靶标：Nuclear factor erythroid 2-related factor 2 External Id：CHEMBL4053417

实验名称：Inhibition of recombinant human PTP1B using pNPP as substrate at 10 uM after 30 mins ... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4053415

实验名称：Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate at 10 uM prei... 来源：ChEMBL 靶标：Tyrosinase External Id：CHEMBL4053412

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hispaglabridin A英文别名

• 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol
• 4-((R)-8,8-Dimethyl-3,4-dihydro-2H,8H-benzo(1,2-b:4,3-b')dipyran-3-yl)-2-(3-methyl-but-2-enyl)-benzene-1,3-diol
• Hispaglabridin A